Rat CD8a Monoclonal Antibody (PE Conjugated) [OX-8](AGEL1256)
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](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/608x608/products/12292/16344/rat-cd8a-monoclonal-antibody-pe-conjugated-ox-8agel1256__41288__98879.1706269884.jpg?c=1 "Rat CD8a Monoclonal Antibody (PE Conjugated) [OX-8](AGEL1256)")
- SKU:
- AGEL1256
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Description
| Antibody Name: | Rat CD8a Monoclonal Antibody (PE Conjugated) |
| Antibody Code: | AGEL1256 |
| Size: | 200 Tests |
| Clone: | OX-8 |
| Synonyms: | T-cell surface glycoprotein CD8 alpha chain,CD8A,T-lymphocyte differentiation antigen T8/Leu-2,MAL |
| Host Species: | Mouse |
| Species Reactivity: | Rat |
| Applications: | FC |
| Concentration: | 5uL |
| Isotype: | IgG2a,k |
| Conjugation: | PE |
| Applications: | FC |
| Recommended Dilution: | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. The amount of the reagent is suggested to be used 5 uL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. |
| Storage Buffer: | PBS with 0.05% Proclin300, 1% BSA |
| Storage: | Store at 2-8°C and protected from prolonged exposure to light. Do not freeze. |
| Gene ID: | 24930 |
| Uniprot: | P07725 |
| Background: | CD8a is a 32 kD glycoprotein also known as T8, Lyt2, Ly-2, and CD8α. CD8a is a member of the immunoglobulin superfamily expressed on most thymocytes, subset of mature T cells, most NK cells, macrophages, and some activated CD4+ T cells (not resting). CD8a forms heterodimers with the CD8β chain (CD8b) on the surface of most thymocytes, while mature peripheral T lymphocytes express almost exclusively the CD8 αβ heterodimer. Intestinal intraepithelial lymphocytes express CD8a without CD8b. CD8 is an antigen co-receptor on T cells that interacts with MHC class I on antigen-presenting cells or epithelial cells. CD8 participates in T cell activation through its association with the T cell receptor complex and protein tyrosine kinase lck (p56lck). |
 | Rat splenocytes are stained with Anti-Rat CD8a Monoclonal Antibody(PE Conjugated)(filled gray histogram). Unstained splenocytes (empty black histogram) are used as control. |