| UniProt Protein Function: | CD2: CD2 interacts with lymphocyte function-associated antigen (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T- cells, the cytoplasmic domain is implicated in the signaling function. Protein type: Apoptosis; Cell surface; Membrane protein, integral Cellular Component: internal side of plasma membrane; cell surface; protein complex; anchored to plasma membrane; integral to membrane; extracellular region; intercellular junction; external side of plasma membrane; lipid raft Molecular Function: protein homodimerization activity; protein self-association; receptor activity; receptor tyrosine kinase binding; glycoprotein binding; protein kinase binding; antigen binding; receptor binding Biological Process: heterotypic cell-cell adhesion; cell-cell adhesion; T cell activation; positive regulation of tumor necrosis factor production |
| UniProt Protein Details: | |
| NCBI Summary: | cell surface antigen involved in T lymphocyte activation and proliferation; interacts with CD5 [RGD, Feb 2006] |
| UniProt Code: | P08921 |
| NCBI GenInfo Identifier: | 6978627 |
| NCBI Gene ID: | 497761 |
| NCBI Accession: | NP_036962.1 |
| UniProt Secondary Accession: | P08921 |
| UniProt Related Accession: | P08921 |
| Molecular Weight: | 38,414 Da |
| NCBI Full Name: | T-cell surface antigen CD2 |
| NCBI Synonym Full Names: | Cd2 molecule |
| NCBI Official Symbol: | Cd2 |
| NCBI Official Synonym Symbols: | CD2R; LFA2; OX34; LFA-2; OX-34 |
| NCBI Protein Information: | T-cell surface antigen CD2 |
| UniProt Protein Name: | T-cell surface antigen CD2 |
| UniProt Synonym Protein Names: | LFA-2; LFA-3 receptor; OX-34 antigen; T-cell surface antigen T11/Leu-5; CD_antigen: CD2 |
| Protein Family: | CD2 |
| UniProt Gene Name: | Cd2 |
| UniProt Entry Name: | CD2_RAT |
