Description
| Product Name: | Rat CD146/MCAM Recombinant Protein (His tag) |
| Product Code: | RPES5908 |
| Size: | 20µg |
| Species: | Rat |
| Expression Host: | E.coli |
| Synonyms: | Cell surface glycoprotein MUC18, MUC18, Mcam, Gicerin, Melanoma cell adhesion molecule, Melanoma-associated antigen MUC18, CD146 |
| Mol Mass: | 21.89 kDa |
| AP Mol Mass: | 30 kDa |
| Tag: | N-His |
| Purity: | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin Level: | Please contact us for more information. |
| Bio Activity: | Testing in progress |
| Sequence: | His 151-Val 350 |
| Accession: | Q9EPF2 |
| Storage: | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation: | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution: | Please refer to the printed manual for detailed information. |
| Background: | Melanomia Cell Adhesion Molecule (MCAM), also known as CD146 and MUC18, is a putative Ig-superfamily adhesion molecule that is expressed on endothelial cells and a variety of tumor cells. MCAM is associated with tumor progression and metastasis and may be involved in embryonic neural development. An alternately spliced isoform of rat MCAM has a 40 residue deletion in the cytoplasmic domain. |