Cytokines Recombinant Proteins

Rat BD 3 Recombinant Protein (RPPB0075)

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SKU:
RPPB0075
Product Type:
Recombinant Protein
Species:
Rat
Uniprot:
Q32ZI4
Research Area:
Cytokines

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:Rat BD 3 Recombinant Protein
Product Code:RPPB0075
Size:20µg
Species:Rat
Target:BD 3
Synonyms:Beta-defensin 3, BD-3, Defensin beta 3, Defb3.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered White lyophilized (freeze-dried) powder.
Formulation:BD-3 protein was lyophilized from a 0.2�m filtered concentrated solution in PBS, pH 7.4.
Solubility:It is recommended to reconstitute the lyophilized BD-3 in sterile 18M-cm H2O not less than 100�g/ml, which can then be further diluted to other aqueous solutions.
Stability:Lyophilized BD-3 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution BD-3 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
Purity:Greater than 98.0% as determined by:(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE.
Amino Acid Sequence:KKVYNAVSCM TNGGICWLKC SGTFREIGSC GTRQLKCCKK K
Biological Activity:Measured by its antimicrobial activity against E. coli. The ED50 for this effect is typically 4-20�g/ml, corresponding to a specific activity of 50,000-250,000units/mg.

Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 103A, which has broad spectrum antimicrobial activity and may play an important role in innate epithelial defense.

BD-3 Rat Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 41 amino acids and having a molecular mass of 4.5kDa.The BD-3 is purified by proprietary chromatographic techniques.

UniProt Protein Function:Has bactericidal activity.
UniProt Protein Details:
NCBI Summary:
UniProt Code:Q32ZI4
NCBI GenInfo Identifier:82830407
NCBI Gene ID:641623
NCBI Accession:NP_001032637.1
UniProt Secondary Accession:Q32ZI4
UniProt Related Accession:Q32ZI4
Molecular Weight:7,082 Da
NCBI Full Name:beta-defensin 3
NCBI Synonym Full Names:beta-defensin 3
NCBI Official Symbol:Defb3��
NCBI Official Synonym Symbols:
NCBI Protein Information:beta-defensin 3; BD-3; defensin, beta 3
UniProt Protein Name:Beta-defensin 3
UniProt Synonym Protein Names:Defensin, beta 3
Protein Family:
UniProt Gene Name:Defb3��
UniProt Entry Name:DEFB3_RAT
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