RASSF7 Antibody (PACO16952)
- SKU:
- PACO16952
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | RASSF7 Antibody (PACO16952) |
| Antibody SKU: | PACO16952 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:25-1:100 |
| Species Reactivity: | Human |
| Immunogen: | Fusion protein of human RASSF7 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Gel: 8%SDS-PAGE, Lysate: 60 μg, Lane: Raji cells, Primary antibody: PACO16952(RASSF7 Antibody) at dilution 1/800, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 seconds. |
 | The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using PACO16952(RASSF7 Antibody) at dilution 1/45, on the right is treated with fusion protein. (Original magnification: x200). |
| Background: | RASSF7 (Ras association domain-containing protein 7), also designated HRAS1-related cluster protein 1, is a 373 amino acid, protein that localizes to the centrosome. RASSF7, RASSF8, RASSF9 and RASSF10 are four evolutionary conserved proteins that are collectively known as the N-terminal RASSF family. Expressed in skin, neural tube and eye, RASSF7 is believed to play an essential role in mitosis. Further supporting its mitotic role, knockdown of Xenopus RASSF7 has been shown to influence cell failure to form mitotic spindle and also cause nuclear breakdown and apoptosis. |
| Synonyms: | Ras association (RalGDS/AF-6) domain family (N-terminal) member 7 |
| UniProt Protein Function: | HRC1: 2 isoforms of the human protein are produced by alternative splicing.Chromosomal Location of Human Ortholog: 11p15.5Molecular Function: protein binding |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q02833 |
| NCBI GenInfo Identifier: | 18202480 |
| NCBI Gene ID: | 8045 |
| NCBI Accession: | Q02833.1 |
| UniProt Secondary Accession: | Q02833,Q3KP41, Q3KP42, G5E9N9 |
| UniProt Related Accession: | Q02833 |
| Molecular Weight: | 34,660 Da |
| NCBI Full Name: | Ras association domain-containing protein 7 |
| NCBI Synonym Full Names: | Ras association domain family member 7 |
| NCBI Official Symbol: | RASSF7 |
| NCBI Official Synonym Symbols: | HRC1; HRAS1; C11orf13 |
| NCBI Protein Information: | ras association domain-containing protein 7 |
| UniProt Protein Name: | Ras association domain-containing protein 7 |
| UniProt Synonym Protein Names: | HRAS1-related cluster protein 1 |
| Protein Family: | Ras association domain-containing protein |
| UniProt Gene Name: | RASSF7 |
| UniProt Entry Name: | RASF7_HUMAN |
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