RASSF3 Antibody (PACO16951)
- SKU:
- PACO16951
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | RASSF3 Antibody (PACO16951) |
| Antibody SKU: | PACO16951 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:30-1:150 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Fusion protein of human RASSF3 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO16951(RASSF3 Antibody) at dilution 1/35, on the right is treated with fusion protein. (Original magnification: x200). |
 | The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using PACO16951(RASSF3 Antibody) at dilution 1/35, on the right is treated with fusion protein. (Original magnification: x200). |
| Background: | The RAS oncogene (MIM 190020) is mutated in nearly one-third of all human cancers. Members of the RAS superfamily are plasma membrane GTP-binding proteins that modulate intracellular signal transduction pathways. A subfamily of RAS effectors, including RASSF3, share a RAS association (RA) domain. |
| Synonyms: | Ras association (RalGDS/AF-6) domain family member 3 |
| UniProt Protein Function: | RASSF3: 2 isoforms of the human protein are produced by alternative splicing.Protein type: Adaptor/scaffoldChromosomal Location of Human Ortholog: 12q14.2Cellular Component: cytoplasm; plasma membraneMolecular Function: identical protein binding; protein binding |
| UniProt Protein Details: | |
| NCBI Summary: | The RAS oncogene (MIM 190020) is mutated in nearly one-third of all human cancers. Members of the RAS superfamily are plasma membrane GTP-binding proteins that modulate intracellular signal transduction pathways. A subfamily of RAS effectors, including RASSF3, share a RAS association (RA) domain.[supplied by OMIM, Jul 2003] |
| UniProt Code: | Q86WH2 |
| NCBI GenInfo Identifier: | 74714093 |
| NCBI Gene ID: | 283349 |
| NCBI Accession: | Q86WH2.1 |
| UniProt Secondary Accession: | Q86WH2,Q86WH1 |
| UniProt Related Accession: | Q86WH2 |
| Molecular Weight: | 10,265 Da |
| NCBI Full Name: | Ras association domain-containing protein 3 |
| NCBI Synonym Full Names: | Ras association domain family member 3 |
| NCBI Official Symbol: | RASSF3 |
| NCBI Official Synonym Symbols: | RASSF5 |
| NCBI Protein Information: | ras association domain-containing protein 3 |
| UniProt Protein Name: | Ras association domain-containing protein 3 |
| UniProt Synonym Protein Names: | |
| Protein Family: | Ras association domain-containing protein |
| UniProt Gene Name: | RASSF3 |
| UniProt Entry Name: | RASF3_HUMAN |
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