RASSF1A Monoclonal Antibody [P3F3AT] (CPAB0547)

Name: RASSF1A Monoclonal Antibody [P3F3AT] (CPAB0547)
SKU: CPAB0547
Availability: OutOfStock

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system_update_alt Datasheet Overview

system_update_alt Datasheet Overview

system_update_alt Datasheet Overview

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Product Name:	RASSF1A Antibody
Product Sku:	CPAB0547
Size:	5μg
Host Species:	Mouse
Immunogen:	Anti-human RASSF1A mAb, is derived from hybridization of mouse SP2/O myeloma cells with spleen cells from BALB/c mice immunized with recombinant human RASSF1A amino acids 1-34 purified from Ecoli.
Clone:	P3F3AT.
Reactivity:	Other bodies
Applications:	Western Blot, ELISA

Purification Method:	RASSF1A antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Isotype:	IgG1
Background:	RASSF1A is a protein similar to the RAS effector proteins. Loss or altered expression of the RASSF1A gene has been linked to the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of the RASSF1A gene. The inactivation of the RASSF1A gene was found to be interconnected with the hypermethylation of its CpG-island promoter region. The RASSF1A protein was found to interact with DNA repair protein XPA. RASSF1A was also shown to inhibit the accumulation of cyclin D1, and thus induce cell cycle arrest.
Synonyms:	Ras association domain-containing protein 1, 123F2, RDA32, NORE2A, RASSF1A, REH3P21, RASSF1.
Storage Buffer:	For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.