RARRES1 Antibody (PACO18984)
- SKU:
- PACO18984
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | RARRES1 Antibody (PACO18984) |
| Antibody SKU: | PACO18984 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:100-1:300 |
| Species Reactivity: | Human |
| Immunogen: | Synthetic peptide of human RARRES1 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using PACO18984(RARRES1 Antibody) at dilution 1/60, on the right is treated with synthetic peptide. (Original magnification: x200). |
 | Gel: 10+15%SDS-PAGE, Lysate: 50 μg, Lane: Human liver cancer tissue, Primary antibody: PACO18984(RARRES1 Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 40 seconds. |
 | The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using PACO18984(RARRES1 Antibody) at dilution 1/60, on the right is treated with synthetic peptide. (Original magnification: x200). |
| Background: | This gene was identified as a retinoid acid, (RA) receptor-responsive gene. It encodes a type 1 membrane protein. The expression of this gene is upregulated by tazarotene as well as by retinoic acid, receptors. The expression of this gene is found to be downregulated in prostate cancer, which is caused by the methylation of its promoter and CpG island. Alternatively spliced transcript variant encoding distinct isoforms have been observed. |
| Synonyms: | Retinoic acid, receptor responder (tazarotene induced) 1 |
| UniProt Protein Function: | RARRES1: identified as a retinoid acid (RA) receptor-responsive gene. It encodes a type 1 membrane protein. The expression of this gene is upregulated by tazarotene as well as by retinoic acid receptors. The expression of this gene is found to be downregulated in prostate cancer, which is caused by the methylation of its promoter and CpG island. Alternatively spliced transcript variant encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]Protein type: Membrane protein, integralChromosomal Location of Human Ortholog: 3q25.32 |
| UniProt Protein Details: | |
| NCBI Summary: | This gene was identified as a retinoid acid (RA) receptor-responsive gene. It encodes a type 1 membrane protein. The expression of this gene is upregulated by tazarotene as well as by retinoic acid receptors. The expression of this gene is found to be downregulated in prostate cancer, which is caused by the methylation of its promoter and CpG island. Alternatively spliced transcript variant encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P49788 |
| NCBI GenInfo Identifier: | 57014141 |
| NCBI Gene ID: | 5918 |
| NCBI Accession: | P49788.2 |
| UniProt Secondary Accession: | P49788,Q8N1D7 |
| UniProt Related Accession: | P49788 |
| Molecular Weight: | 25,812 Da |
| NCBI Full Name: | Retinoic acid receptor responder protein 1 |
| NCBI Synonym Full Names: | retinoic acid receptor responder 1 |
| NCBI Official Symbol: | RARRES1 |
| NCBI Official Synonym Symbols: | LXNL; TIG1; PERG-1 |
| NCBI Protein Information: | retinoic acid receptor responder protein 1 |
| UniProt Protein Name: | Retinoic acid receptor responder protein 1 |
| UniProt Synonym Protein Names: | Phorbol ester-induced gene 1 protein; PERG-1; RAR-responsive protein TIG1; Tazarotene-induced gene 1 protein |
| Protein Family: | Retinoic acid receptor responder protein |
| UniProt Gene Name: | RARRES1 |
| UniProt Entry Name: | TIG1_HUMAN |
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