Description
| Antibody Name: | RAP1GDS1 Antibody (PACO11718) |
| Antibody SKU: | PACO11718 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Human RAP1GDS1 |
| Form: | Liquid |
| Storage Buffer: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| Purification Method: | Antigen Affinity Purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | RAP1, GTP-GDP dissociation stimulator 1;RAP1GDS1;GDS1;MGC118859;MGC118861;SmgGDS ; |
| UniProt Protein Function: | RAP1GDS1: Stimulates GDP/GTP exchange reaction of a group of small GTP-binding proteins (G proteins) including Rap1a/Rap1b, RhoA, RhoB and KRas, by stimulating the dissociation of GDP from and the subsequent binding of GTP to each small G protein. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:GEFs, misc.; GEFs Chromosomal Location of Human Ortholog: 4q23-q25 Cellular Component: cytosol; endoplasmic reticulum; mitochondrion Molecular Function:protein binding Biological Process: elevation of mitochondrial calcium ion concentration; positive regulation of GTPase activity; reduction of endoplasmic reticulum calcium ion concentration; small GTPase mediated signal transduction |
| NCBI Summary: | The smg GDP dissociation stimulator (smgGDS) protein is a stimulatory GDP/GTP exchange protein with GTPase activity (Riess et al., 1993 [PubMed 8262526]).[supplied by OMIM, Feb 2010] |
| UniProt Code: | P52306 |
| NCBI GenInfo Identifier: | 212276504 |
| NCBI Gene ID: | 5910 |
| NCBI Accession: | P52306.3 |
| UniProt Secondary Accession: | P52306,Q499L7, Q4KMV2, Q4QQI8, Q9BUW9, Q9BUX6, Q9NYM2 Q9NZA8, E9PH06, G5E9P9, |
| UniProt Related Accession: | P52306 |
| Molecular Weight: | 56,536 Da |
| NCBI Full Name: | Rap1 GTPase-GDP dissociation stimulator 1 |
| NCBI Synonym Full Names: | Rap1 GTPase-GDP dissociation stimulator 1 |
| NCBI Official Symbol: | RAP1GDS1 |
| NCBI Official Synonym Symbols: | GDS1; SmgGDS |
| NCBI Protein Information: | rap1 GTPase-GDP dissociation stimulator 1 |
| UniProt Protein Name: | Rap1 GTPase-GDP dissociation stimulator 1 |
| UniProt Synonym Protein Names: | Exchange factor smgGDS; SMG GDS protein; SMG P21 stimulatory GDP/GTP exchange protein |
| Protein Family: | Rap1 GTPase-GDP dissociation stimulator |
| UniProt Gene Name: | RAP1GDS1 |
| UniProt Entry Name: | GDS1_HUMAN |