Description
Product Name: | RAP1B Polyclonal Antibody |
Product Code: | CAB24472 |
Reactivity: | Human, Rat |
Applications: | Western blotting |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Reactivity: | Human, Rat |
Tested Applications: | WB, ELISA |
Key Applications: | Western blotting |
Recommended Dilution: | WB 1:100-1:500 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
Positive Samples: | Rat brain |
Cellular Location: | Cell junction, Cell membrane, Cytoplasm, cytosol |
This gene encodes a member of the RAS-like small GTP-binding protein superfamily. Members of this family regulate multiple cellular processes including cell adhesion and growth and differentiation. This protein localizes to cellular membranes and has been shown to regulate integrin-mediated cell signaling. This protein also plays a role in regulating outside-in signaling in platelets. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 3, 5, 6 and 9.
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 81-181 of human RAP1B (NP_056461.1). |
Sequence: | VYSIT AQSTF NDLQD LREQI LRVKD TDDVP MILVG NKCDL EDERV VGKEQ GQNLA RQWNN CAFLE SSAKS KINVN EIFYD LVRQI NRKTP VPGKA RKKSS C |
Synonyms: | RAP1B, K-REV, RAL1B, ras-related protein Rap-1b |
Calculated MW: | 15kDa/16kDa/18kDa/20kDa |
Observed MW: | 23kDa |