RANBP17 Antibody (PACO61189)
- SKU:
- PACO61189
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | RANBP17 Antibody (PACO61189) |
| Antibody SKU: | PACO61189 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Ran-binding protein 17 protein (465-587AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | IHC image of PACO61189 diluted at 1:100 and staining in paraffin-embedded human liver cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
 | Western Blot. Positive WB detected in: A549 whole cell lysate. All lanes: RANBP17 antibody at 3.9µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 125, 66 kDa. Observed band size: 125 kDa. |
| Background: | May function as a nuclear transport receptor. |
| Synonyms: | Ran-binding protein 17, RANBP17 |
| UniProt Protein Function: | RANBP17: May function as a nuclear transport receptor. Belongs to the exportin family.Protein type: Nuclear export; Nuclear importChromosomal Location of Human Ortholog: 5q34Cellular Component: cytoplasm; nuclear poreMolecular Function: nuclear export signal receptor activity; Ran GTPase bindingBiological Process: protein export from nucleus |
| UniProt Protein Details: | |
| NCBI Summary: | The transport of protein and large RNAs through the nuclear pore complexes (NPC) is an energy-dependent and regulated process. The import of proteins with a nuclear localization signal (NLS) is accomplished by recognition of one or more clusters of basic amino acids by the importin-alpha/beta complex; see MIM 600685 and MIM 602738. The small GTPase RAN (MIM 601179) plays a key role in NLS-dependent protein import. RAN-binding protein-17 is a member of the importin-beta superfamily of nuclear transport receptors.[supplied by OMIM, Jul 2002] |
| UniProt Code: | Q9H2T7 |
| NCBI GenInfo Identifier: | 17368945 |
| NCBI Gene ID: | 64901 |
| NCBI Accession: | Q9H2T7.1 |
| UniProt Secondary Accession: | Q9H2T7,Q8IU74 |
| UniProt Related Accession: | Q9H2T7 |
| Molecular Weight: | 65,567 Da |
| NCBI Full Name: | Ran-binding protein 17 |
| NCBI Synonym Full Names: | RAN binding protein 17 |
| NCBI Official Symbol: | RANBP17 |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | ran-binding protein 17 |
| UniProt Protein Name: | Ran-binding protein 17 |
| UniProt Synonym Protein Names: | |
| Protein Family: | Ran-binding protein |
| UniProt Gene Name: | RANBP17 |
| UniProt Entry Name: | RBP17_HUMAN |
| Antibodies |
| RANBP17 Antibody (PACO05064) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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