RAD9A Antibody (PACO04862)
- SKU:
- PACO04862
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | RAD9A Antibody |
| Antibody SKU: | PACO04862 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | IHC:1:100-1:300 |
| Species Reactivity: | Human |
| Immunogen: | synthesized peptide derived from human Rad9 around the non-phosphorylation site of S272. |
| Form: | Liquid |
| Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | RAD9A; Cell cycle checkpoint control protein RAD9A; hRAD9; DNA repair exonuclease rad9 homolog A |
| UniProt Protein Function: | Rad9: a cell cycle checkpoint protein required for cell cycle arrest and DNA damage repair in response to DNA damage. Possesses a 3' to 5' exonuclease activity, which may contribute to its role in sensing and repairing DNA damage. Forms a checkpoint protein complex with RAD1 and HUS1. This complex is recruited by checkpoint protein RAD17 to the sites of DNA damage, which is thought to be important for triggering the checkpoint-signaling cascade. Use of alternative polyA sites has been noted for Rad9.Protein type: EC 3.1.11.2; DNA replication; Deoxyribonuclease; Apoptosis; Cell cycle regulationChromosomal Location of Human Ortholog: 11q13.1-q13.2Cellular Component: nucleoplasm; cytoplasm; nucleusMolecular Function: protein binding; enzyme binding; histone deacetylase binding; exodeoxyribonuclease III activity; 3'-5' exonuclease activity; SH3 domain binding; protein kinase bindingBiological Process: intra-S DNA damage checkpoint; DNA damage checkpoint; DNA replication checkpoint; DNA replication; DNA repair; DNA catabolic process, exonucleolytic; response to DNA damage stimulus |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q96C41 |
| NCBI GenInfo Identifier: | 4759022 |
| NCBI Gene ID: | 5883 |
| NCBI Accession: | NP_004575 |
| UniProt Secondary Accession: | Q96C41,Q6FI29, Q96C41, B2RCZ8 |
| UniProt Related Accession: | Q96C41,Q99638 |
| Molecular Weight: | 42,547 Da |
| NCBI Full Name: | cell cycle checkpoint control protein RAD9A isoform 1 |
| NCBI Synonym Full Names: | RAD9 homolog A (S. pombe) |
| NCBI Official Symbol: | RAD9A |
| NCBI Official Synonym Symbols: | RAD9 |
| NCBI Protein Information: | cell cycle checkpoint control protein RAD9A; DNA repair exonuclease rad9 homolog A; hRAD9 |
| UniProt Protein Name: | Cell cycle checkpoint control protein RAD9A |
| UniProt Synonym Protein Names: | DNA repair exonuclease rad9 homolog A |
| Protein Family: | RAD9, HUS1, RAD1-interacting nuclear orphan protein |
| UniProt Gene Name: | RAD9A |
| UniProt Entry Name: | RAD9A_HUMAN |
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