RABL2A Antibody (PACO22539)
- SKU:
- PACO22539
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | RABL2A Antibody (PACO22539) |
| Antibody SKU: | PACO22539 |
| Size: | 100ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:3000 |
| Species Reactivity: | Human |
| Immunogen: | Synthesized peptide derived from internal of human RABL2A. |
| Form: | Liquid |
| Storage Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot analysis of extracts from HuvEc and COLO205 cells, using RABL2A antibody. |
| Background: | Plays an essential role in male fertility, sperm intra-flagellar transport, and tail assembly. Binds, in a GTP-regulated manner, to a specific set of effector proteins including key proteins involved in cilia development and function and delivers them into the growing sperm tail By similarity. |
| Synonyms: | Rab-like protein 2A; |
| UniProt Protein Function: | RABL2A: a member of the RAB gene family which belongs to the RAS GTPase superfamily. The proteins in the family of RAS-related signaling molecules are small GTP-binding proteins that play important roles in the regulation of exocytotic and endocytotic pathways. This gene maps to the site of an ancestral telomere fusion event and may be a subtelomeric gene. Two alternatively spliced transcript variants have been identified, both encoding the same protein. [provided by RefSeq, Jul 2008]Protein type: G protein, monomeric, Rab; G protein; G protein, monomericChromosomal Location of Human Ortholog: 2q13Cellular Component: intracellularMolecular Function: GTP binding; GTPase activity; protein bindingBiological Process: small GTPase mediated signal transduction |
| UniProt Protein Details: | |
| NCBI Summary: | This gene is a member of the RAB gene family which belongs to the RAS GTPase superfamily. The proteins in the family of RAS-related signaling molecules are small GTP-binding proteins that play important roles in the regulation of exocytotic and endocytotic pathways. This gene maps to the site of an ancestral telomere fusion event and may be a subtelomeric gene. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015] |
| UniProt Code: | Q9UBK7 |
| NCBI GenInfo Identifier: | 12643870 |
| NCBI Gene ID: | 11159 |
| NCBI Accession: | Q9UBK7.1 |
| UniProt Secondary Accession: | Q9UBK7,Q9NU37, B7ZBD6 |
| UniProt Related Accession: | Q9UBK7 |
| Molecular Weight: | 27,201 Da |
| NCBI Full Name: | Rab-like protein 2A |
| NCBI Synonym Full Names: | RAB, member of RAS oncogene family-like 2A |
| NCBI Official Symbol: | RABL2A |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | rab-like protein 2A |
| UniProt Protein Name: | Rab-like protein 2A |
| UniProt Synonym Protein Names: | |
| Protein Family: | |
| UniProt Gene Name: | RABL2A |
| UniProt Entry Name: | RBL2A_HUMAN |
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