RABGEF1 Polyclonal Antibody
- SKU:
- CAB20789
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | RABGEF1 Polyclonal Antibody |
| Product Code: | CAB20789 |
| Reactivity: | Human |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:2000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Customer Validation: | IF(Homo sapiens) |
RABGEF1 forms a complex with rabaptin-5 (RABPT5; MIM 603616) that is required for endocytic membrane fusion, and it serves as a specific guanine nucleotide exchange factor (GEF) for RAB5 (RAB5A; MIM 179512) (Horiuchi et al., 1997 [PubMed 9323142]).
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 222-491 of human RABGEF1 (NP_055319.1). |
| Sequence: | YVFCP ETTDD EKKDL AIQKR IRALR WVTPQ MLCVP VNEDI PEVSD MVVKA ITDII EMDSK RVPRD KLACI TKCSK HIFNA IKITK NEPAS ADDFL PTLIY IVLKG NPPRL QSNIQ YITRF CNPSR LMTGE DGYYF TNLCC AVAFI EKLDA QSLNL SQEDF DRYMS GQTSP RKQEA ESWSP DACLG VKQMY KNLDL LSQLN ERQER IMNEA KKLEK DLIDW TDGIA REVQD IVEKY PLEIK PPNQP LAAID SENVE NDKLP PPLQP QVYAG |
| Synonyms: | RAP1, RABEX5, rabex-5 |
| Calculated MW: | 68kDa |
| Observed MW: | Refer to figures |
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