Rabbit TNF-alpha/TNFSF2/TNFa Recombinant Protein (RPES3618)
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- SKU:
- RPES3618
- Product Type:
- Recombinant Protein
- Species:
- Rabbit
Description
system_update_altDatasheet
Rabbit TNF-alpha/TNFSF2/TNFa Recombinant Protein
Tumor necrosis factor alpha (TNF?) is the prototypic ligand of the TNF superfamily. TNF? forms a homotrimer and functions by activating two types of receptors TNF-R1 (TNF receptor type 1,p55R) and TNF-R2 (TNF receptor type 2,p75R). TNF? is a pleiotropic cytokine that is capable to promote inflammation, to induce apoptotic cell death, and to inhibit tumorigenesis and viral replication. TNF? is a potent lymphoid factor that exerts cytotoxic effects on a wide range of tumor cells and certain other target cells.
| Product Name: | Rabbit TNF-alpha/TNFSF2/TNFa Recombinant Protein (RPES3618) |
| Product Code: | RPES3618 |
| Size: | 10µg |
| Species: | Rabbit |
| Expressed Host: | E.coli |
| Synonyms: | Tumor Necrosis Factor, Cachectin, TNF-Alpha, Tumor Necrosis Factor Ligand Superfamily Member 2, TNF-a, TNF, TNFA, TNFSF2 |
| Accession: | P04924 |
| Sequence: | Val77-Leu235 |
| Activity: | Measured in a cytotoxicity assay using L?929 mouse fibroblast cells in the presence of the metabolic inhibitor actinomycin D. The ED50 for this effect is 3.5 pg/ml. |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Rabbit TNFa is produced by our E.coli expression system and the target gene encoding Val77-Leu235 is expressed. |
| Purity: | > 95% as determined by reducing SDS-PAGE. |
| Mol Mass: | 17.59 kDa |
| AP Mol Mass: | 18 kDa |
| Formulation: | Lyophilized from a 0.2 µm filtered solution of 20mM PB, 300mM NaCl, pH7.4. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
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