Antibody Name:	RAB41 Antibody (PACO17517)
Antibody SKU:	PACO17517
Size:	50ul
Host Species:	Rabbit
Tested Applications:	ELISA, IHC
Recommended Dilutions:	ELISA:1:2000-1:10000, IHC:1:100-1:200
Species Reactivity:	Human
Immunogen:	Synthetic peptide of human RAB41

Form:	Liquid
Storage Buffer:	-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:	Antigen affinity purification
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Non-conjugated

	The image is immunohistochemistry of paraffin-embedded Human renal cancer tissue using PACO17517(RAB41 Antibody) at dilution 1/100. (Original magnification: x200).
	The image is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using PACO17517(RAB41 Antibody) at dilution 1/100. (Original magnification: x200).

Background:

This gene encodes a small GTP-binding protein that belongs to the largest family within the Ras superfamily. These proteins function as regulators of membrane trafficking. They cycle between inactive GDP-bound and activated GTP-bound states, which is controlled by GTP hydrolysis-activating proteins (GAPs). This family member can be activated by the GAP protein RN-Tre, and it is localized to the Golgi complex.

Synonyms:

Ras-related protein Rab-41

UniProt Protein Function:	RAB41: a small GTP-binding protein that belongs to the largest family within the Ras superfamily. These proteins function as regulators of membrane trafficking. They cycle between inactive GDP-bound and activated GTP-bound states, which is controlled by GTP hydrolysis-activating proteins (GAPs). This family member can be activated by the GAP protein RN-Tre, and it is localized to the Golgi complex. [provided by RefSeq, May 2010]Protein type: G protein, monomeric, Rab; G protein; G protein, monomericChromosomal Location of Human Ortholog: Xq13.1Cellular Component: Golgi apparatus; Golgi membraneMolecular Function: protein bindingBiological Process: intra-Golgi vesicle-mediated transport; retrograde transport, endosome to Golgi; retrograde vesicle-mediated transport, Golgi to ER
UniProt Protein Details:
NCBI Summary:	This gene encodes a small GTP-binding protein that belongs to the largest family within the Ras superfamily. These proteins function as regulators of membrane trafficking. They cycle between inactive GDP-bound and activated GTP-bound states, which is controlled by GTP hydrolysis-activating proteins (GAPs). This family member can be activated by the GAP protein RN-Tre, and it is localized to the Golgi complex. [provided by RefSeq, May 2010]
UniProt Code:	Q5JT25
NCBI GenInfo Identifier:	229462781
NCBI Gene ID:	347517
NCBI Accession:	Q5JT25.2
UniProt Secondary Accession:	Q5JT25,Q17RQ0
UniProt Related Accession:	Q5JT25
Molecular Weight:	24,939 Da
NCBI Full Name:	Ras-related protein Rab-41
NCBI Synonym Full Names:	RAB41, member RAS oncogene family
NCBI Official Symbol:	RAB41
NCBI Official Synonym Symbols:
NCBI Protein Information:	ras-related protein Rab-41
UniProt Protein Name:	Ras-related protein Rab-41
UniProt Synonym Protein Names:
Protein Family:	Ras-related protein
UniProt Gene Name:	RAB41
UniProt Entry Name:	RAB41_HUMAN