RAB40B Antibody (PACO35438)
- SKU:
- PACO35438
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | RAB40B Antibody (PACO35438) |
| Antibody SKU: | PACO35438 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Ras-related protein Rab-40B protein (1-278AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human brain tissue using PACO35438 at dilution of 1:100. |
| Background: | May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. |
| Synonyms: | Ras-related protein Rab-40B (SOCS box-containing protein RAR) (Protein Rar), RAB40B, SEC4L |
| UniProt Protein Function: | RAB40B: May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Belongs to the small GTPase superfamily. Rab family.Protein type: G protein; G protein, monomeric; G protein, monomeric, RabChromosomal Location of Human Ortholog: 17q25.3Cellular Component: plasma membrane; endosome membraneMolecular Function: GTPase activity; GDP binding; GTP bindingBiological Process: regulation of exocytosis; intracellular protein transport; protein secretion; protein ubiquitination; Rab protein signal transduction; vesicle docking during exocytosis |
| UniProt Protein Details: | |
| NCBI Summary: | The protein encoded by this gene has similarity to a yeast protein which suggests a role of the gene product in regulating secretory vesicles. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q12829 |
| NCBI GenInfo Identifier: | 5803163 |
| NCBI Gene ID: | 10966 |
| NCBI Accession: | NP_006813.1 |
| UniProt Secondary Accession: | Q12829,Q8WVG3 |
| UniProt Related Accession: | Q12829 |
| Molecular Weight: | 30,956 Da |
| NCBI Full Name: | ras-related protein Rab-40B |
| NCBI Synonym Full Names: | RAB40B, member RAS oncogene family |
| NCBI Official Symbol: | RAB40B |
| NCBI Official Synonym Symbols: | RAR; SEC4L |
| NCBI Protein Information: | ras-related protein Rab-40B; protein Rar; SOCS box-containing protein RAR; GTP-binding protein homologous to Saccharomyces cerevisiae SEC4 |
| UniProt Protein Name: | Ras-related protein Rab-40B |
| UniProt Synonym Protein Names: | SOCS box-containing protein RAR |
| Protein Family: | Ras-related protein |
| UniProt Gene Name: | RAB40B |
| UniProt Entry Name: | RB40B_HUMAN |
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