Description
Antibody Name: | RAB40AL Antibody (PACO59876) |
Antibody SKU: | PACO59876 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, IF |
Recommended Dilutions: | ELISA:1:2000-1:10000, IF:1:20-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Ras-related protein Rab-40A-like protein (1-88AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Immunofluorescence staining of MCF-7 cells with PACO59876 at 1:33, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
Background: | May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. |
Synonyms: | Ras-related protein Rab-40A-like (Ras-like GTPase), RAB40AL, RLGP |
UniProt Protein Function: | |
UniProt Protein Details: | |
NCBI Summary: | This gene encodes a member of the Rab40 subfamily of Rab small GTP-binding proteins that contains a C-terminal suppressors of cytokine signaling box. Disruptions in this gene are associated with Duchenne muscular dystrophy. [provided by RefSeq, Apr 2010] |
UniProt Code: | P0C0E4 |
NCBI GenInfo Identifier: | 73611940 |
NCBI Gene ID: | 282808 |
NCBI Accession: | NP_001027004.1 |
UniProt Secondary Accession: | P0C0E4 |
UniProt Related Accession: | P0C0E4 |
Molecular Weight: | |
NCBI Full Name: | ras-related protein Rab-40A-like |
NCBI Synonym Full Names: | RAB40A like |
NCBI Official Symbol: | RAB40AL |
NCBI Official Synonym Symbols: | RAR2; RLGP; MRXSMP |
NCBI Protein Information: | ras-related protein Rab-40A-like |
UniProt Protein Name: | Ras-related protein Rab-40A-like |
UniProt Synonym Protein Names: | Ras-like GTPase |
Protein Family: | |
UniProt Gene Name: | RAB40AL |
UniProt Entry Name: | RB40L_HUMAN |