RAB3IL1 Antibody (PACO38598)
- SKU:
- PACO38598
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | RAB3IL1 Antibody (PACO38598) |
| Antibody SKU: | PACO38598 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA |
| Recommended Dilutions: | |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Guanine nucleotide exchange factor for Rab-3A protein (1-200AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Background: | Guanine nucleotide exchange factor (GEF) which may activate RAB3A, a GTPase that regulates synaptic vesicle exocytosis. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. May also activate RAB8A and RAB8B. |
| Synonyms: | Guanine nucleotide exchange factor for Rab-3A (Rab-3A-interacting-like protein 1) (Rab3A-interacting-like protein 1) (Rabin3-like 1), RAB3IL1 |
| UniProt Protein Function: | RAB3IL1: Guanine nucleotide exchange factor (GEF) for Rab3A, a GTPase that regulates synaptic vesicle exocytosis. Belongs to the SEC2 family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: GEFs, Rab; GEFsChromosomal Location of Human Ortholog: 11q12.2Molecular Function: protein binding; Rab guanyl-nucleotide exchange factor activity |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a guanine nucleotide exchange factor for the ras-related protein Rab3A. The encoded protein binds Rab3a and the inositol hexakisphosphate kinase InsP6K1. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 7. [provided by RefSeq, Nov 2012] |
| UniProt Code: | Q8TBN0 |
| NCBI GenInfo Identifier: | 74730489 |
| NCBI Gene ID: | 5866 |
| NCBI Accession: | Q8TBN0.1 |
| UniProt Secondary Accession: | Q8TBN0,Q86V32, Q9P1Q8 |
| UniProt Related Accession: | Q8TBN0 |
| Molecular Weight: | 39,791 Da |
| NCBI Full Name: | Guanine nucleotide exchange factor for Rab-3A |
| NCBI Synonym Full Names: | RAB3A interacting protein like 1 |
| NCBI Official Symbol: | RAB3IL1 |
| NCBI Official Synonym Symbols: | GRAB |
| NCBI Protein Information: | guanine nucleotide exchange factor for Rab-3A |
| UniProt Protein Name: | Guanine nucleotide exchange factor for Rab-3A |
| UniProt Synonym Protein Names: | Rab-3A-interacting-like protein 1; Rab3A-interacting-like protein 1; Rabin3-like 1 |
| Protein Family: | Guanine nucleotide exchange factor |
| UniProt Gene Name: | RAB3IL1 |
| UniProt Entry Name: | R3GEF_HUMAN |
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