Description
Antibody Name: | RAB3C Antibody (PACO17551) |
Antibody SKU: | PACO17551 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:2000, IHC:1:25-1:100 |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Synthetic peptide of human RAB3c |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Human fetal brain tissue, 293T cells, Primary antibody: PACO17551(RAB3c Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute. | |
The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using PACO17551(RAB3c Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: x200). |
Background: | Ras-related protein Rab-3C is a protein that in humans is encoded by the RAB3C gene.RAB proteins, such as RAB3C, are small GTPases implicated in the regulation of vesicular trafficking between membrane compartments.It involved in rotein transport and vesicular traffic probably. |
Synonyms: | Ras-related protein Rab-3C |
UniProt Protein Function: | RAB3C: Protein transport. Probably involved in vesicular traffic. Belongs to the small GTPase superfamily. Rab family. |
UniProt Protein Details: | Protein type:G protein; G protein, monomeric, Rab; G protein, monomeric Chromosomal Location of Human Ortholog: 5q13 Cellular Component: synaptic vesicle; secretory granule membrane; perinuclear region of cytoplasm; plasma membrane; cytosol; vesicle; endosome Molecular Function:GTPase activity; protein binding; GDP binding; GTP binding; myosin V binding Biological Process: regulation of exocytosis; intracellular protein transport; antigen processing and presentation; synaptic vesicle exocytosis; metabolic process; protein secretion; Rab protein signal transduction; vesicle docking during exocytosis |
NCBI Summary: | This gene is a member of the RAS oncogene family and encodes a small GTPase. Other similar small GTPases are known to be involved in vesicle trafficking, and the encoded protein was shown to play a role in recycling phagocytosed MHC class 1 complexes to the cell surface. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015] |
UniProt Code: | Q96E17 |
NCBI GenInfo Identifier: | 23396832 |
NCBI Gene ID: | 115827 |
NCBI Accession: | Q96E17.1 |
UniProt Related Accession: | Q96E17 |
Molecular Weight: | |
NCBI Full Name: | Ras-related protein Rab-3C |
NCBI Synonym Full Names: | RAB3C, member RAS oncogene family |
NCBI Official Symbol: | RAB3C |
NCBI Protein Information: | ras-related protein Rab-3C |
UniProt Protein Name: | Ras-related protein Rab-3C |
Protein Family: | Ras-related protein |
UniProt Gene Name: | RAB3C |
UniProt Entry Name: | RAB3C_HUMAN |
Antibodies |
RAB3C Antibody (PACO11657) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |