RAB30 Antibody (PACO35326)
- SKU:
- PACO35326
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | RAB30 Antibody (PACO35326) |
| Antibody SKU: | PACO35326 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Ras-related protein Rab-30 protein (1-200AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | Antigen Affinity Purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot. All lanes: RAB30 antibody at 1µg/ml + Hela whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 24, 19 kDa. Observed band size: 19 kDa. |
 | Immunohistochemistry of paraffin-embedded human pancreatic tissue using PACO35326 at dilution of 1:100. |
| Background: | The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion (By similarity). Required for maintaining the structural integrity of the Golgi apparatus, possibly by mediating interactions with cytoplasmic scaffolding proteins. |
| Synonyms: | Ras-related protein Rab-30, RAB30 |
| UniProt Protein Function: | RAB30: Belongs to the small GTPase superfamily. Rab family.Protein type: G protein, monomeric, Rab; G protein, monomericChromosomal Location of Human Ortholog: 11q14.1Cellular Component: Golgi cisterna; Golgi stack; cis-Golgi network; membrane; cytoplasm; trans-Golgi networkMolecular Function: GTPase activity; GDP binding; GTP bindingBiological Process: intracellular protein transport; metabolic process; Rab protein signal transduction; Golgi organization and biogenesis |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q15771 |
| NCBI GenInfo Identifier: | 554506503 |
| NCBI Gene ID: | 27314 |
| NCBI Accession: | NP_001272988.1 |
| UniProt Secondary Accession: | Q15771,Q6FGK1, Q6MZH2, Q96CI8 |
| UniProt Related Accession: | Q15771 |
| Molecular Weight: | |
| NCBI Full Name: | ras-related protein Rab-30 |
| NCBI Synonym Full Names: | RAB30, member RAS oncogene family |
| NCBI Official Symbol: | RAB30 |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | ras-related protein Rab-30 |
| UniProt Protein Name: | Ras-related protein Rab-30 |
| UniProt Synonym Protein Names: | |
| Protein Family: | Ras-related protein |
| UniProt Gene Name: | RAB30 |
| UniProt Entry Name: | RAB30_HUMAN |
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