RAB11FIP2 Antibody (PACO22537)
- SKU:
- PACO22537
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | RAB11FIP2 Antibody (PACO22537) |
| Antibody SKU: | PACO22537 |
| Size: | 100ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:3000 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Synthesized peptide derived from internal of human RAB11FIP2. |
| Form: | Liquid |
| Storage Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot analysis of extracts from A549 cells, COLO cells, HUVEC cells and MCF-7 cells, using RAB11FIP2 antibody. |
| Background: | A Rab11 effector binding preferentially phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and phosphatidic acid (PA) and acting in the regulation of the transport of vesicles from the endosomal recycling compartment (ERC) to the plasma membrane. Involved in insulin granule exocytosis. Also involved in receptor-mediated endocytosis and membrane trafficking of recycling endosomes, probably originating from clathrin-coated vesicles. Required in a complex with MYO5B and RAB11 for the transport of NPC1L1 to the plasma membrane. Also acts as a regulator of cell polarity. |
| Synonyms: | KIAA0941; NRip11; Rab11 family-interacting protein 2; Rab11-FIP2; RFIP2 |
| UniProt Protein Function: | A Rab11 effector binding preferentially phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and phosphatidic acid (PA) and acting in the regulation of the transport of vesicles from the endosomal recycling compartment (ERC) to the plasma membrane. Involved in insulin granule exocytosis. Also involved in receptor-mediated endocytosis and membrane trafficking of recycling endosomes, probably originating from clathrin-coated vesicles. Required in a complex with MYO5B and RAB11 for the transport of NPC1L1 to the plasma membrane. Also acts as a regulator of cell polarity. |
| UniProt Code: | Q7L804 |
| NCBI GenInfo Identifier: | 1054343429 |
| NCBI Gene ID: | 22841 |
| NCBI Accession: | NP_001317096.1 |
| UniProt Secondary Accession: | Q7L804,Q3I768, Q9Y2F0, A6NEI4, |
| UniProt Related Accession: | Q7L804 |
| Molecular Weight: | 58 KD |
| NCBI Full Name: | rab11 family-interacting protein 2 isoform 2 |
| NCBI Synonym Full Names: | RAB11 family interacting protein 2 |
| NCBI Official Symbol: | RAB11FIP2 |
| NCBI Official Synonym Symbols: | nRip11; Rab11-FIP2 |
| NCBI Protein Information: | rab11 family-interacting protein 2 |
| UniProt Protein Name: | Rab11 family-interacting protein 2 |
| UniProt Synonym Protein Names: | NRip11 |
| Protein Family: | Rab11 family-interacting protein |
| UniProt Gene Name: | RAB11FIP2 |
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