Description
Antibody Name: | R3HCC1L Antibody (PACO23436) |
Antibody SKU: | PACO23436 |
Size: | 100ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:3000, IHC:1:50-1:100 |
Species Reactivity: | Human, Mouse |
Immunogen: | Synthesized peptide derived from internal of human GIDRP88. |
Form: | Liquid |
Storage Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western blot analysis of extracts from Jurkat cells and COS cells, using GIDRP88 antibody. | |
Immunohistochemistry analysis of paraffin-embedded human tesophagusis tissue using GIDRP88 antibody. |
Background: | 3 isoforms of the human protein are produced by alternative splicing. |
Synonyms: | GIDRP; GIDRP86; growth inhibition and differentiation-related 88; mitochondrial space protein 32.1; PSORT |
UniProt Protein Function: | This potassium channel may be involved in the regulation of insulin secretion by glucose and/or neurotransmitters acting through G-protein-coupled receptors. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. |
UniProt Protein Details: | |
NCBI Summary: | |
UniProt Code: | Q7Z5L2 |
NCBI GenInfo Identifier: | 375298727 |
NCBI Gene ID: | 27291 |
NCBI Accession: | NP_001243548 |
UniProt Secondary Accession: | Q7Z5L2 |
UniProt Related Accession: | Q7Z5L2 |
Molecular Weight: | 87kDa |
NCBI Full Name: | coiled-coil domain-containing protein R3HCC1L isoform 1 |
NCBI Synonym Full Names: | R3H domain and coiled-coil containing 1 like |
NCBI Official Symbol: | R3HCC1L |
NCBI Official Synonym Symbols: | PSORT; GIDRP86; GIDRP88; C10orf28 |
NCBI Protein Information: | coiled-coil domain-containing protein R3HCC1L |
UniProt Protein Name: | G protein-activated inward rectifier potassium channel 2 |
UniProt Synonym Protein Names: | BIR1; Inward rectifier K(+) channel Kir3.2; KATP-2; Potassium channel, inwardly rectifying subfamily J member 6 |
Protein Family: | G protein-activated inward rectifier potassium channel |
UniProt Gene Name: | KCNJ6 |
UniProt Entry Name: |
Antibodies |
R3HCC1L Antibody (PACO03892) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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