Purified Anti-Mouse IL-17A Antibody [17F3]

(No reviews yet) Write a Review
SKU:
AGEL3512
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
ICFCM
Reactivity:
Mouse
Host Species:
Mouse
Isotype:
Mouse IgG1, k
Clone:
17F3
Conjugation:
Unconjugated

Description

Product Name:Purified Anti-Mouse IL-17A Antibody [17F3]
Product Code:AGEL3512
Size:25ug, 100ug
Clone No:17F3
Synonyms:Interleukin-17A, Il17a, Ctla9
Reactivity:Mouse
Host Species:Mouse
Applications:ICFCM
Isotype:Mouse IgG1, κ
Isotype Control:Purified Mouse IgG1, κ Isotype Control [MOPC-21]
Conjugation:Unconjugated
Applications:ICFCM
Recommended Dilution:Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer.
Storage:Keep as concentrated solution. Store at 2-8°C. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Shipping:Biological ice pack at 4°C
Form:Liquid
Gene ID:16171
Swissprot:Q62386
Background Information:The 17F3 monoclonal antibody reacts with mouse IL-17A a 15-20 kDa cytokine expressed by Th17 cells, γδ T cells, iNKT cells, NK cells, LTi cells, neutrophils, and intestinal Paneth cells. IL-17A has pleiotropic effects in immunoregulation and inflammation. It plays an important role in anti-microbial and chronic inflammation by inducing cytokine and chemokine production, neutrophil influx, and the production of antibacterial peptides but it is also an inflammatory mediator in the development of autoimmune diseases including rheumatoid arthritis, asthma, multiple sclerosis, and psoriasis. The 17F3 antibody has been shown to neutralize IL-18A in vivo.
View AllClose

0 Reviews

View AllClose

Related Products