Purified Anti-Mouse CD38 Antibody [NIMR5]
- SKU:
- AGEL2362
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Applications:
- FCM
- Reactivity:
- Mouse
- Host Species:
- Rat
- Isotype:
- Rat IgG2a, κ
- Clone:
- NIMR5
- Conjugation:
- Unconjugated
Description
Product Name: | Purified Anti-Mouse CD38 Antibody [NIMR5] |
Product Code: | AGEL2362 |
Clone No: | NIMR5 |
Synonyms: | ADP-ribosyl cyclase 1,ADPRC 1,CD38,NIM-R5 antigen,2'-phospho-cyclic-ADP-ribose transferase |
Reactivity: | Mouse |
Host Species: | Rat |
Applications: | FCM |
Isotype: | Rat IgG2a, κ |
Isotype Control: | Purified Rat IgG2a, κ Isotype Control [2A3] (AGEL2653) |
Conjugation: | Unconjugated |
Form: | Liquid |
Recommended Use: | Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. |
Storage Buffer: | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer. |
Swissprot: | P56528 |
Stability & Storage: | Keep as concentrated solution. Store at 2-8°C. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase. |
Shipping: | Biological ice pack at 4°C |
CD38 is a 42 kD glycoprotein, also known as T10. It is an ADP-ribosyl hydrolase, expressed on B cells, NK cells, a subset of T cells, brain, muscle, and kidney. In mouse, CD38 expression is downregulated on germinal center B cells and plasma cells, whereas this is not the case for humans. By functioning as both a cyclase and a hydrolase, CD38 mediates lymphocyte activation, as well as adhesion and metabolism of cADPR and NAADP. CD31 is the ligand of CD38.