Purified Anti-Human/Mouse IL-5 Antibody [TRFK5]
- SKU:
- AGEL2382
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Applications:
- ICFCM
- Applications:
- ELISA
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rat
- Isotype:
- Rat IgG1, κ
- Clone:
- TRFK5
- Conjugation:
- Unconjugated
Description
Product Name: | Purified Anti-Human/Mouse IL-5 Antibody [TRFK5] |
Product Code: | AGEL2382 |
Clone No: | TRFK5 |
Synonyms: | Interleukin-5,IL-5,B-cell differentiation factor I,T-cell replacing factor,TRF |
Reactivity: | Human,Mouse |
Host Species: | Rat |
Applications: | ICFCM, ELISA |
Isotype: | Rat IgG1, κ |
Isotype Control: | Purified Rat IgG1, κ Isotype Control [HRPN] (AGEL2629) |
Conjugation: | Unconjugated |
Form: | Liquid |
Recommended Use: | Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. |
Storage Buffer: | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer. |
Swissprot: | P05113,P04401 |
Stability & Storage: | Keep as concentrated solution. Store at 2-8°C. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase. |
Shipping: | Biological ice pack at 4°C |
IL-5 is a homodimeric, disulphide-linked protein produced by T-cells. Monomeric human IL-5 is a 126 amino acid protein with a reported molecular weight of 26 kD for the homodimeric protein. Mouse and human IL-5 are approximately 70% identical. IL-5 has been shown to promote the growth of immature hematopoietic BFU-E progenitors, stimulate the activation and differentiation of eosinophils, and promote the generation of cytotoxic lymphocytes. Mouse IL-5 induces the differentiation and proliferation of pre-activated B-cells and stimulates the production and secretion of IgM and IgA by B-cells stimulated with bacterial endotoxin. The TRFK5 antibody can neutralize the bioactivity of natural or recombinant IL-5.