Purified Anti-Human CD7 Antibody [124-1D1]
- SKU:
- AGEL3038
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Applications:
- FCM
- Reactivity:
- Human
- Host Species:
- Mouse
- Isotype:
- Mouse IgG1, κ
- Clone:
- 124-1D1
- Conjugation:
- Unconjugated
Description
| Product Name: | Purified Anti-Human CD7 Antibody [124-1D1] |
| Product Code: | AGEL3038 |
| Clone No: | 124-1D1 |
| Synonyms: | T-cell antigen CD7,CD7,GP40,T-cell leukemia antigen,T-cell surface antigen Leu-9,TP41,TP41 |
| Reactivity: | Human |
| Host Species: | Mouse |
| Applications: | FCM |
| Isotype: | Mouse IgG1, κ |
| Isotype Control: | Purified Mouse IgG1, κ Isotype Control [MOPC-21] (AGEL2560) |
| Conjugation: | Unconjugated |
| Form: | Liquid |
| Recommended Use: | Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. |
| Storage Buffer: | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer. |
| Swissprot: | P09564 |
| Stability & Storage: | Keep as concentrated solution. Store at 2-8°C. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase. |
| Shipping: | Biological ice pack at 4°C |
CD7 is a 40 kD type I transmembrane glycoprotein also known as gp40. It is a member of the immunoglobulin superfamily found on T cells, NK cells, thymocytes, hematopoietic progenitors, and monocytes (weakly). CD7 is also expressed on acute lymphocytic leukemia (ALL) and some acute myeloid leukemia (AML) cells. CD7 crosslinking induces a calcium flux in T lymphocytes, presumably as a result of cytoplasmic domain association with PI3-kinase. CD7 costimulation can induce cytokine secretion and modulate cellular adhesion.
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