Purified Anti-Human CD45RO Antibody [UCHL1]

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SKU:
AGEL3509
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Human
Host Species:
Mouse
Isotype:
Mouse IgG2a, k
Clone:
UCHL1
Conjugation:
Unconjugated

Description

Product Name:Purified Anti-Human CD45RO Antibody [UCHL1]
Product Code:AGEL3509
Size:25ug, 100ug
Clone No:UCHL1
Reactivity:Human
Host Species:Mouse
Applications:FCM
Isotype:Mouse IgG2a, κ
Isotype Control:Purified Mouse IgG2a, κ Isotype Control [C1.18.4]
Conjugation:Unconjugated
Applications:FCM
Recommended Dilution:Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer.
Storage:Keep as concentrated solution. Store at 2-8°C. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Shipping:Biological ice pack at 4°C
Form:Liquid
Gene ID:5788
Background Information:CD45RO is a 180 kD single chain membrane glycoprotein. It is a splice variant of tyrosine phosphatase CD45, lacking the A, B, and C determinants. The CD45RO isoform is expressed on activated and memory T cells, some B cell subsets, activated monocytes/macrophages, and granulocytes. CD45RO enhances both T cell receptor and B cell receptor signaling mediated activation. CD45 and its isoforms non-covalently associate with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4. CD45 has also been reported to bind galectin-1 and CD22. CD45 isoform expression can change in response to cytokines.
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