Purified Anti-Human CD44 Antibody [Hermes-1]
- SKU:
- AGEL2405
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Applications:
- FCM
- Reactivity:
- Human
- Host Species:
- Rat
- Isotype:
- Rat IgG2a, κ
- Clone:
- Hermes-1
- Conjugation:
- Unconjugated
Description
| Product Name: | Purified Anti-Human CD44 Antibody [Hermes-1] |
| Product Code: | AGEL2405 |
| Clone No: | Hermes-1 |
| Synonyms: | LHR,PGP-I,CDw44,Epican,HUTCH-I |
| Reactivity: | Human |
| Host Species: | Rat |
| Applications: | FCM |
| Isotype: | Rat IgG2a, κ |
| Isotype Control: | Purified Rat IgG2a, κ Isotype Control [2A3] (AGEL2653) |
| Conjugation: | Unconjugated |
| Form: | Liquid |
| Recommended Use: | Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. |
| Storage Buffer: | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer. |
| Swissprot: | P16070 |
| Stability & Storage: | Keep as concentrated solution. Store at 2-8°C. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase. |
| Shipping: | Biological ice pack at 4°C |
CD44 is a 80-95 kD glycoprotein also known as Hermes, Pgp1, H-CAM, or HUTCH. It is expressed on all leukocytes, endothelial cells, hepatocytes, and mesenchymal cells. As B and T cells become activated or progress to the memory stage, CD44 expression increases from a low or mid level of intensity to high expression levels. Thus, CD44 has been reported to be a valuable marker for memory cell subsets. CD44 is an adhesion molecule involved in leukocyte attachment to and rolling on endothelial cells, homing to peripheral lymphoid organs and to the sites of inflammation, and leukocyte aggregation.
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