Purified Anti-Human CD16 Antibody [3G8]

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SKU:
AGEL3348
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Applications:
Block
Reactivity:
Human
Host Species:
Mouse
Isotype:
Mouse IgG1, k
Clone:
3G8
Conjugation:
Unconjugated

Description

Product Name:Purified Anti-Human CD16 Antibody [3G8]
Product Code:AGEL3348
Size:25ug, 100ug
Clone No:3G8
Synonyms:FcγRIII, Fc gamma receptor, Fc gamma receptor 3
Reactivity:Human
Host Species:Mouse
Applications:FCM,Block
Isotype:Mouse IgG1, κ
Isotype Control:Purified Mouse IgG1, κ Isotype Control [MOPC-21]
Conjugation:Unconjugated
Applications:FCM,Block
Recommended Dilution:Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.5 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer.
Storage:Keep as concentrated solution. Store at 2-8°C. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Shipping:Biological ice pack at 4°C
Form:Liquid
Gene ID:941
Swissprot:P08637,O75015
Background Information:CD16 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD16 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD16 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD16 appears to be expressed later in the immune response than CD86. CD16 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.
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