Name: pth Antibody (PACO34766)
SKU: PACO34766
Availability: OutOfStock

Antibody Name:	pth Antibody (PACO34766)
Antibody SKU:	PACO34766
Size:	50ug
Host Species:	Rabbit
Tested Applications:	ELISA
Recommended Dilutions:
Species Reactivity:	Escherichia coli
Immunogen:	Recombinant Escherichia coli Peptidyl-tRNA hydrolase protein (1-194AA)

Form:	Liquid
Storage Buffer:	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method:	>95%, Protein G purified
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Non-conjugated

Background:	The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Involved in lambda inhibition of host protein synthesis. PTH activity may, directly or indirectly, be the target for lambda bar RNA leading to rap cell death.
Synonyms:	Peptidyl-tRNA hydrolase (PTH) (EC 3.1.1.29), pth

UniProt Protein Function:	The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Involved in lambda inhibition of host protein synthesis. PTH activity may, directly or indirectly, be the target for lambda bar RNA leading to rap cell death.
UniProt Protein Details:
NCBI Summary:	Histidine 20 acts as the catalytic base during hydrolysis. [More information is available at EcoGene: EG10785]. Peptidyl-tRNA hydrolase is essential for growth in Escherichia coli. lysV, a lysine acceptor tRNA, was found to be a multicopy suppressor of a temperature sensitive pth mutant, indicating that the pth mutant phenotype is due to starvation for Lys-tRNA(Lys) . [More information is available at EcoCyc: EG10785].
UniProt Code:	P0A7D1
NCBI GenInfo Identifier:	16129167
NCBI Gene ID:	945765
NCBI Accession:	NP_415722.1
UniProt Secondary Accession:	P0A7D1,P23932
UniProt Related Accession:	P0A7D1
Molecular Weight:	21,082 Da
NCBI Full Name:	peptidyl-tRNA hydrolase
NCBI Synonym Full Names:
NCBI Official Symbol:	pth
NCBI Official Synonym Symbols:	asuA; ECK1192; JW1195; rap
NCBI Protein Information:	peptidyl-tRNA hydrolase
UniProt Protein Name:	Peptidyl-tRNA hydrolase
UniProt Synonym Protein Names:
Protein Family:	Parathyroid hormone
UniProt Gene Name:	pth
UniProt Entry Name:	PTH_ECOLI