PTGR2 Antibody (PACO11575)
- SKU:
- PACO11575
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | PTGR2 Antibody (PACO11575) |
| Antibody SKU: | PACO11575 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Human PTGR2 |
| Form: | Liquid |
| Storage Buffer: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| Purification Method: | Antigen Affinity purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | prostaglandin reductase 2;PTGR2;DKFZp686P10120;FLJ39091;FLJ99229;PGR2;ZADH1 ; |
| UniProt Protein Function: | PTGR2: Functions as 15-oxo-prostaglandin 13-reductase and acts on 15-keto-PGE1, 15-keto-PGE2, 15-keto-PGE1-alpha and 15-keto- PGE2-alpha with highest activity towards 15-keto-PGE2. Overexpression represses transcriptional activity of PPARG and inhibits adipocyte differentiation. Belongs to the NADP-dependent oxidoreductase L4BD family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: EC 1.3.1.48; OxidoreductaseChromosomal Location of Human Ortholog: 14q24.3Molecular Function: 15-oxoprostaglandin 13-oxidase activity; zinc ion bindingBiological Process: prostaglandin metabolic process |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes an enzyme involved in the metabolism of prostaglandins. The encoded protein catalyzes the NADPH-dependent conversion of 15-keto-prostaglandin E2 to 15-keto-13,14-dihydro-prostaglandin E2. This protein may also be involved in regulating activation of the peroxisome proliferator-activated receptor. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009] |
| UniProt Code: | Q8N8N7 |
| NCBI GenInfo Identifier: | 62901454 |
| NCBI Gene ID: | 145482 |
| NCBI Accession: | Q8N8N7.1 |
| UniProt Secondary Accession: | Q8N8N7,Q3L8A4, Q6MZH8 |
| UniProt Related Accession: | Q8N8N7 |
| Molecular Weight: | 19,675 Da |
| NCBI Full Name: | Prostaglandin reductase 2 |
| NCBI Synonym Full Names: | prostaglandin reductase 2 |
| NCBI Official Symbol: | PTGR2 |
| NCBI Official Synonym Symbols: | PGR2; ZADH1; HEL-S-298 |
| NCBI Protein Information: | prostaglandin reductase 2 |
| UniProt Protein Name: | Prostaglandin reductase 2 |
| UniProt Synonym Protein Names: | 15-oxoprostaglandin 13-reductase; Zinc-binding alcohol dehydrogenase domain-containing protein 1 |
| Protein Family: | Prostaglandin reductase |
| UniProt Gene Name: | PTGR2 |
| UniProt Entry Name: | PTGR2_HUMAN |
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