Name: PTGR2 Antibody (PACO02495)
SKU: PACO02495
Availability: OutOfStock

Antibody Name:	PTGR2 Antibody
Antibody SKU:	PACO02495
Size:	50ug
Host Species:	Rabbit
Tested Applications:	ELISA, WB, IHC
Recommended Dilutions:	WB:1:500-1:2000, IHC:1:100-1:300
Species Reactivity:	Human
Immunogen:	synthesized peptide derived from the Internal region of human PTGR2.

Form:	Liquid
Storage Buffer:	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Non-conjugated

Synonyms:

PTGR2; ZADH1; Prostaglandin reductase 2; PRG-2; 15-oxoprostaglandin 13-reductase; Zinc-binding alcohol dehydrogenase domain-containing protein 1

UniProt Protein Function:	PTGR2: Functions as 15-oxo-prostaglandin 13-reductase and acts on 15-keto-PGE1, 15-keto-PGE2, 15-keto-PGE1-alpha and 15-keto- PGE2-alpha with highest activity towards 15-keto-PGE2. Overexpression represses transcriptional activity of PPARG and inhibits adipocyte differentiation. Belongs to the NADP-dependent oxidoreductase L4BD family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: EC 1.3.1.48; OxidoreductaseChromosomal Location of Human Ortholog: 14q24.3Molecular Function: 15-oxoprostaglandin 13-oxidase activity; zinc ion bindingBiological Process: prostaglandin metabolic process
UniProt Protein Details:
NCBI Summary:	This gene encodes an enzyme involved in the metabolism of prostaglandins. The encoded protein catalyzes the NADPH-dependent conversion of 15-keto-prostaglandin E2 to 15-keto-13,14-dihydro-prostaglandin E2. This protein may also be involved in regulating activation of the peroxisome proliferator-activated receptor. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009]
UniProt Code:	Q8N8N7
NCBI GenInfo Identifier:	62901454
NCBI Gene ID:	145482
NCBI Accession:	Q8N8N7.1
UniProt Secondary Accession:	Q8N8N7,Q3L8A4, Q6MZH8
UniProt Related Accession:	Q8N8N7
Molecular Weight:	19,675 Da
NCBI Full Name:	Prostaglandin reductase 2
NCBI Synonym Full Names:	prostaglandin reductase 2
NCBI Official Symbol:	PTGR2
NCBI Official Synonym Symbols:	PGR2; ZADH1; HEL-S-298
NCBI Protein Information:	prostaglandin reductase 2
UniProt Protein Name:	Prostaglandin reductase 2
UniProt Synonym Protein Names:	15-oxoprostaglandin 13-reductase; Zinc-binding alcohol dehydrogenase domain-containing protein 1
Protein Family:	Prostaglandin reductase
UniProt Gene Name:	PTGR2
UniProt Entry Name:	PTGR2_HUMAN