Description
| Antibody Name: | PTBP3 Antibody (PACO11886) |
| Antibody SKU: | PACO11886 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Human ROD1 |
| Form: | Liquid |
| Storage Buffer: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| Purification Method: | Antigen Affinity purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | ROD1 regulator of differentiation 1 (S. pombe);ROD1;DKFZp781I1117;PTBP3 ; |
| UniProt Protein Function: | ROD1: RNA-binding protein that mediates pre-mRNA alternative splicing regulation. Plays a role in the regulation of cell proliferation, differentiation and migration. Positive regulator of EPO-dependent erythropoiesis. Participates in cell differentiation regulation by repressing tissue-specific exons. Promotes FAS exon 6 skipping. Binds RNA, preferentially to both poly(G) and poly(U). 6 isoforms of the human protein are produced by alternative splicing.Protein type: RNA-bindingChromosomal Location of Human Ortholog: 9q32Molecular Function: RNA bindingBiological Process: anatomical structure morphogenesis; negative regulation of RNA splicing |
| UniProt Protein Details: | |
| NCBI Summary: | The protein encoded by this gene binds RNA and is a regulator of cell differentiation. The encoded protein preferentially binds to poly(G) and poly(U) sequences in vitro. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011] |
| UniProt Code: | O95758 |
| NCBI GenInfo Identifier: | 218511814 |
| NCBI Gene ID: | 9991 |
| NCBI Accession: | O95758.2 |
| UniProt Secondary Accession: | O95758,Q68DB9, Q86YB3, Q86YH9, B1ALY2, B1ALY3, B1ALY5 B1ALY6, B3KME7 |
| UniProt Related Accession: | O95758 |
| Molecular Weight: | 49,540 Da |
| NCBI Full Name: | Polypyrimidine tract-binding protein 3 |
| NCBI Synonym Full Names: | polypyrimidine tract binding protein 3 |
| NCBI Official Symbol: | PTBP3 |
| NCBI Official Synonym Symbols: | ROD1 |
| NCBI Protein Information: | polypyrimidine tract-binding protein 3 |
| UniProt Protein Name: | Polypyrimidine tract-binding protein 3 |
| UniProt Synonym Protein Names: | Regulator of differentiation 1; Rod1 |
| Protein Family: | Polypyrimidine tract-binding protein |
| UniProt Gene Name: | PTBP3 |
| UniProt Entry Name: | PTBP3_HUMAN |