PSD4 Antibody (PACO39138)
- SKU:
- PACO39138
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | PSD4 Antibody (PACO39138) |
| Antibody SKU: | PACO39138 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human PH and SEC7 domain-containing protein 4 protein (1-300AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human tonsil tissue using PACO39138 at dilution of 1:100. |
 | Immunohistochemistry of paraffin-embedded human breast cancer using PACO39138 at dilution of 1:100. |
| Background: | Guanine nucleotide exchange factor for ARF6 and ARL14/ARF7. Through ARL14 activation, controls the movement of MHC class II-containing vesicles along the actin cytoskeleton in dendritic cells. Involved in membrane recycling. Interacts with several phosphatidylinositol phosphate species, including phosphatidylinositol 3,4-bisphosphate, phosphatidylinositol 3,5-bisphosphate and phosphatidylinositol 4,5-bisphosphate. |
| Synonyms: | PH and SEC7 domain-containing protein 4 (Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6 B) (Exchange factor for ARF6 B) (Pleckstrin homology and SEC7 domain-containing protein 4) (Telomeric of interleukin-1 cluster protein), PSD4, EFA6B TIC |
| UniProt Protein Function: | PSD4: Guanine nucleotide exchange factor for ARF6 and ARL14/ARF7. Through ARL14 activation, controls the movement of MHC class II-containing vesicles along the actin cytoskeleton in dendritic cells. Involved in membrane recycling. Interacts with several phosphatidylinositol phosphate species, including phosphatidylinositol 3,4-bisphosphate, phosphatidylinositol 3,5- bisphosphate and phosphatidylinositol 4,5-bisphosphate. 2 isoforms of the human protein are produced by alternative splicing.Protein type: GEFs; GEFs, ARFChromosomal Location of Human Ortholog: 2q13Cellular Component: membrane |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q8NDX1 |
| NCBI GenInfo Identifier: | 56788370 |
| NCBI Gene ID: | 23550 |
| NCBI Accession: | NP_036587.2 |
| UniProt Secondary Accession: | Q8NDX1,O95621, Q4ZG34, Q6GPH8, Q8IYP4, A6NEG7, A8K1Y0 |
| UniProt Related Accession: | Q8NDX1 |
| Molecular Weight: | 116kDa |
| NCBI Full Name: | PH and SEC7 domain-containing protein 4 |
| NCBI Synonym Full Names: | pleckstrin and Sec7 domain containing 4 |
| NCBI Official Symbol: | PSD4 |
| NCBI Official Synonym Symbols: | TIC; EFA6B |
| NCBI Protein Information: | PH and SEC7 domain-containing protein 4 |
| UniProt Protein Name: | PH and SEC7 domain-containing protein 4 |
| UniProt Synonym Protein Names: | Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6 B; Exchange factor for ARF6 B; Pleckstrin homology and SEC7 domain-containing protein 4; Telomeric of interleukin-1 cluster protein |
| Protein Family: | PH and SEC7 domain-containing protein |
| UniProt Gene Name: | PSD4 |
| UniProt Entry Name: | PSD4_HUMAN |
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