Description
Antibody Name: | Psat1 Antibody (PACO40318) |
Antibody SKU: | PACO40318 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA |
Recommended Dilutions: | |
Species Reactivity: | Mouse |
Immunogen: | Recombinant Mouse Phosphoserine aminotransferase protein (1-370AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Background: | Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine. |
Synonyms: | Phosphoserine aminotransferase (PSAT) (EC 2.6.1.52) (Endometrial progesterone-induced protein) (EPIP) (Phosphohydroxythreonine aminotransferase), Psat1, Psa Psat |
UniProt Protein Function: | PSAT1: Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. Defects in PSAT1 are the cause of phosphoserine aminotransferase deficiency (PSATD). PSATD is characterized biochemically by low plasma and cerebrospinal fluid concentrations of serine and glycine and clinically by intractable seizures, acquired microcephaly, hypertonia, and psychomotor retardation. Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Amino Acid Metabolism - glycine, serine and threonine; Cofactor and Vitamin Metabolism - vitamin B6; EC 2.6.1.52; TransferaseChromosomal Location of Human Ortholog: 19 A|19 10.86 cMCellular Component: cytoplasm; cytosolMolecular Function: phosphoserine transaminase activityBiological Process: L-serine biosynthetic process |
UniProt Protein Details: | |
NCBI Summary: | |
UniProt Code: | Q99K85 |
NCBI GenInfo Identifier: | 54292132 |
NCBI Gene ID: | 107272 |
NCBI Accession: | NP_803155.1 |
UniProt Secondary Accession: | Q99K85 |
UniProt Related Accession: | Q99K85 |
Molecular Weight: | 56.47kD |
NCBI Full Name: | phosphoserine aminotransferase isoform 1 |
NCBI Synonym Full Names: | phosphoserine aminotransferase 1 |
NCBI Official Symbol: | Psat1 |
NCBI Official Synonym Symbols: | PSA; EPIP; Psat; D8Ertd814e |
NCBI Protein Information: | phosphoserine aminotransferase |
UniProt Protein Name: | Phosphoserine aminotransferase |
UniProt Synonym Protein Names: | Endometrial progesterone-induced protein; EPIP; Phosphohydroxythreonine aminotransferase |
Protein Family: | Phosphoserine aminotransferase |
UniProt Gene Name: | Psat1 |
UniProt Entry Name: |