PRUNE Antibody (PACO11512)
- SKU:
- PACO11512
Description
| Antibody Name: | PRUNE Antibody (PACO11512) |
| Antibody SKU: | PACO11512 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC, IF |
| Recommended Dilutions: | |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Human PRUNE |
| Form: | Liquid |
| Storage Buffer: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| Purification Method: | Antigen Affinity purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | prune homolog (Drosophila);PRUNE;DRES-17;HTCD37 ; |
| UniProt Protein Function: | PRUNE: Phosphodiesterase (PDE) that has higher activity toward cAMP than cGMP, as substrate. Plays a role in cell proliferation, is able to induce cell motility and acts as a negative regulator of NME1. Belongs to the PPase class C family. Prune subfamily. 7 isoforms of the human protein are produced by alternative splicing.Protein type: Hydrolase; EC 3.6.1.1; Nucleotide Metabolism - purineChromosomal Location of Human Ortholog: 1q21Cellular Component: cytoplasmMolecular Function: protein binding |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a member of the DHH protein superfamily of phosphoesterases. This protein has been found to function as both a nucleotide phosphodiesterase and an exopolyphosphatase. This protein is believed to stimulate cancer progression and metastases through the induction of cell motility. A pseuodgene has been identified on chromosome 13. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014] |
| UniProt Code: | Q86TP1 |
| NCBI GenInfo Identifier: | 229462737 |
| NCBI Gene ID: | 58497 |
| NCBI Accession: | Q86TP1.2 |
| UniProt Secondary Accession: | Q86TP1,Q5SZF9, Q659E5, Q6P4E0, Q8N654, Q96JU5, Q9C071 Q9C072, Q9UIV0, B2RCH8 |
| UniProt Related Accession: | Q86TP1 |
| Molecular Weight: | 24,475 Da |
| NCBI Full Name: | Protein prune homolog |
| NCBI Synonym Full Names: | prune exopolyphosphatase |
| NCBI Official Symbol: | PRUNE1 |
| NCBI Official Synonym Symbols: | PRUNE; DRES17; HTCD37; DRES-17; H-PRUNE |
| NCBI Protein Information: | protein prune homolog |
| UniProt Protein Name: | Protein prune homolog |
| UniProt Synonym Protein Names: | Drosophila-related expressed sequence 17; DRES-17; DRES17; HTcD37 |
| Protein Family: | Protein prune |
| UniProt Gene Name: | PRUNE |
| UniProt Entry Name: | PRUNE_HUMAN |
Additional Information
Product Type: |
Antibody |
Reactivity: |
Human |
Reactivity: |
Mouse |
Reactivity: |
Rat |
Host Species: |
Rabbit |
Isotype: |
IgG |
Applications: |
ELISA |
Applications: |
WB |
Applications: |
IHC |
Applications: |
IF |
Antibody Type: |
Polyclonal Antibody |
Conjugation: |
Unconjugated |
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