Description
| Antibody Name: | PRTFDC1 Antibody (PACO42234) |
| Antibody SKU: | PACO42234 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Phosphoribosyltransferase domain-containing protein 1 (2-225AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
![]() | Immunohistochemistry of paraffin-embedded human testis tissue using PACO42234 at dilution of 1:100. |
![]() | Immunohistochemistry of paraffin-embedded human ovarian cancer using PACO42234 at dilution of 1:100. |
| Background: | Has low, barely detectable phosphoribosyltransferase activity (in vitro). Binds GMP, IMP and alpha-D-5-phosphoribosyl 1-pyrophosphate (PRPP). Is not expected to contribute to purine metabolism or GMP salvage. |
| Synonyms: | Phosphoribosyltransferase domain-containing protein 1, PRTFDC1, HHGP |
| UniProt Protein Function: | PRTFDC1: Has low, barely detectable phosphoribosyltransferase activity (in vitro). Binds GMP, IMP and alpha-D-5-phosphoribosyl 1-pyrophosphate (PRPP). Is not expected to contribute to purine metabolism or GMP salvage. Belongs to the purine/pyrimidine phosphoribosyltransferase family. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 10p12.1 Cellular Component: cytosol Molecular Function:hypoxanthine phosphoribosyltransferase activity; magnesium ion binding; protein binding; protein homodimerization activity Biological Process: adenine salvage; GMP catabolic process; GMP salvage; guanine salvage; hypoxanthine metabolic process; IMP salvage |
| UniProt Code: | Q9NRG1 |
| NCBI GenInfo Identifier: | 74752920 |
| NCBI Gene ID: | 56952 |
| NCBI Accession: | Q9NRG1.1 |
| UniProt Secondary Accession: | Q9NRG1,Q53HA7, Q59EL9, Q5VV18, Q5VV20, B7Z1Z3, |
| UniProt Related Accession: | Q9NRG1 |
| Molecular Weight: | 19,983 Da |
| NCBI Full Name: | Phosphoribosyltransferase domain-containing protein 1 |
| NCBI Synonym Full Names: | phosphoribosyl transferase domain containing 1 |
| NCBI Official Symbol: | PRTFDC1 |
| NCBI Official Synonym Symbols: | HHGP |
| NCBI Protein Information: | phosphoribosyltransferase domain-containing protein 1 |
| UniProt Protein Name: | Phosphoribosyltransferase domain-containing protein 1 |
| Protein Family: | Phosphoribosyltransferase domain-containing protein |
| UniProt Gene Name: | PRTFDC1 |
| UniProt Entry Name: | PRDC1_HUMAN |
| Antibodies |
| PRTFDC1 Antibody (PACO11511) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |

