Description
Antibody Name: | PRTFDC1 Antibody (PACO42234) |
Antibody SKU: | PACO42234 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Phosphoribosyltransferase domain-containing protein 1 (2-225AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Immunohistochemistry of paraffin-embedded human testis tissue using PACO42234 at dilution of 1:100. |
![]() | Immunohistochemistry of paraffin-embedded human ovarian cancer using PACO42234 at dilution of 1:100. |
Background: | Has low, barely detectable phosphoribosyltransferase activity (in vitro). Binds GMP, IMP and alpha-D-5-phosphoribosyl 1-pyrophosphate (PRPP). Is not expected to contribute to purine metabolism or GMP salvage. |
Synonyms: | Phosphoribosyltransferase domain-containing protein 1, PRTFDC1, HHGP |
UniProt Protein Function: | PRTFDC1: Has low, barely detectable phosphoribosyltransferase activity (in vitro). Binds GMP, IMP and alpha-D-5-phosphoribosyl 1-pyrophosphate (PRPP). Is not expected to contribute to purine metabolism or GMP salvage. Belongs to the purine/pyrimidine phosphoribosyltransferase family. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Chromosomal Location of Human Ortholog: 10p12.1 Cellular Component: cytosol Molecular Function:hypoxanthine phosphoribosyltransferase activity; magnesium ion binding; protein binding; protein homodimerization activity Biological Process: adenine salvage; GMP catabolic process; GMP salvage; guanine salvage; hypoxanthine metabolic process; IMP salvage |
UniProt Code: | Q9NRG1 |
NCBI GenInfo Identifier: | 74752920 |
NCBI Gene ID: | 56952 |
NCBI Accession: | Q9NRG1.1 |
UniProt Secondary Accession: | Q9NRG1,Q53HA7, Q59EL9, Q5VV18, Q5VV20, B7Z1Z3, |
UniProt Related Accession: | Q9NRG1 |
Molecular Weight: | 19,983 Da |
NCBI Full Name: | Phosphoribosyltransferase domain-containing protein 1 |
NCBI Synonym Full Names: | phosphoribosyl transferase domain containing 1 |
NCBI Official Symbol: | PRTFDC1 |
NCBI Official Synonym Symbols: | HHGP |
NCBI Protein Information: | phosphoribosyltransferase domain-containing protein 1 |
UniProt Protein Name: | Phosphoribosyltransferase domain-containing protein 1 |
Protein Family: | Phosphoribosyltransferase domain-containing protein |
UniProt Gene Name: | PRTFDC1 |
UniProt Entry Name: | PRDC1_HUMAN |
Antibodies |
PRTFDC1 Antibody (PACO11511) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |