Prss1 Antibody (PACO29208)
- SKU:
- PACO29208
- Product Type:
- Antibody
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | Prss1 Antibody (PACO29208) |
| Antibody SKU: | PACO29208 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA |
| Recommended Dilutions: | |
| Species Reactivity: | Rat |
| Immunogen: | Recombinant Rat Anionic trypsin-1 protein (24-246AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Background: | extracellular space, serine-type endopeptidase activity, digestion, proteolysis, response to caffeine, response to nicotine, response to nutrient, response to organic substance |
| Synonyms: | Anionic trypsin-1 (EC 3.4.21.4) (Anionic trypsin I) (Pretrypsinogen I) (Serine protease 1), Prss1, Try1 |
| UniProt Protein Function: | trypsin 1: Has activity against the synthetic substrates Boc-Phe- Ser-Arg-Mec, Boc-Leu-Thr-Arg-Mec, Boc-Gln-Ala-Arg-Mec and Boc-Val- Pro-Arg-Mec. The single-chain form is more active than the two- chain form against all of these substrates. Defects in PRSS1 are a cause of pancreatitis (PCTT). A disease characterized by the presence of calculi in pancreatic ducts. It causes severe abdominal pain attacks. Belongs to the peptidase S1 family. |
| UniProt Protein Details: | Protein type:EC 3.4.21.4; Protease; Secreted; Secreted, signal peptide Chromosomal Location of Human Ortholog: 4q23 Cellular Component: extracellular region; extracellular space Molecular Function:calcium ion binding; serine-type endopeptidase activity Biological Process: collagen catabolic process; digestion; proteolysis; response to caffeine; response to nicotine; response to nutrient; response to organic substance |
| NCBI Summary: | catalyzes the cleavage of Arg-Xaa, Lys-Xaa [RGD, Feb 2006] |
| UniProt Code: | P00762 |
| NCBI GenInfo Identifier: | 6981420 |
| NCBI Gene ID: | 24691 |
| NCBI Accession: | NP_036767.1 |
| UniProt Related Accession: | P00762 |
| Molecular Weight: | 39.59kD |
| NCBI Full Name: | anionic trypsin-1 |
| NCBI Synonym Full Names: | protease, serine 1 |
| NCBI Official Symbol: | Prss1 |
| NCBI Official Synonym Symbols: | Try1; PTRYI; RATPTRYI |
| NCBI Protein Information: | anionic trypsin-1 |
| UniProt Protein Name: | Anionic trypsin-1 |
| UniProt Synonym Protein Names: | Anionic trypsin I; Pretrypsinogen I; Serine protease 1 |
| Protein Family: | Anionic trypsin |
| UniProt Gene Name: | Prss1 |
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