PRPS1 Polyclonal Antibody
- SKU:
- CAB21571
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | PRPS1 Polyclonal Antibody |
| Product Code: | CAB21571 |
| Reactivity: | Human |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:2000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Cellular Location: | cytoplasm, cytosol |
This gene encodes an enzyme that catalyzes the phosphoribosylation of ribose 5-phosphate to 5-phosphoribosyl-1-pyrophosphate, which is necessary for purine metabolism and nucleotide biosynthesis. Defects in this gene are a cause of phosphoribosylpyrophosphate synthetase superactivity, Charcot-Marie-Tooth disease X-linked recessive type 5 and Arts Syndrome. Two transcript variants encoding different isoforms have been found for this gene.
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 250-322 of human PRPS1 (NP_002755.1). |
| Sequence: | HGIFS GPAIS RINNA CFEAV VVTNT IPQED KMKHC SKIQV IDISM ILAEA IRRTH NGESV SYLFS HVPL |
| Synonyms: | ARTS, DFN2, PRSI, CMTX5, DFNX1, PRS-I, PPRibP |
| Calculated MW: | 35kDa |
| Observed MW: | Refer to figures |
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