Pro-MMP9 Monoclonal Antibody

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SKU:
CAB23919
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Applications:
WB

Description

Product Name:Pro-MMP9 Monoclonal Antibody
Product Code:CAB23919
Reactivity:Mouse
Applications:Western blotting
Host Species:Rabbit
Purification Method:Affinity purification
Isotype:IgG
Clone No:ARC62081
Reactivity:Mouse
Tested Applications:WB, ELISA
Key Applications:Western blotting
Recommended Dilution:WB 1:500-1:1000
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3.
Positive Samples:Mouse Pro-MMP9 protein
Cellular Location:Secreted, Extracellular space, Extracellular matrix.

This gene encodes a member of the matrix metalloproteinase family of extracellular matrix-degrading enzymes that are involved in tissue remodeling, wound repair, progression of atherosclerosis and tumor invasion. The encoded preproprotein undergoes proteolytic processing to generate a mature, zinc-dependent endopeptidase enzyme that degrades collagens of type IV, V and XI, and elastin. Mice lacking the encoded protein exhibit an abnormal pattern of skeletal growth plate vascularization and ossification, reduced keratinocyte hyperproliferation at all neoplastic stages, a decreased incidence of invasive tumors, and resistance to experimental autoimmune encephalomyelitis.

Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 20-107 of mouse MMP9(NP_038627.1).
Sequence:APYQR QPTFV VFPKD LKTSN LTDTQ LAEAY LYRYG YTRAA QMMGE KQSLR PALLM LQKQL SLPQT GELDS QTLKA IRTPR CGVPD VGR
Synonyms:Clg4b, Gel B, MMP-9, B/MMP9, pro-MMP-9
Calculated MW:80KDa
Observed MW:40kDa
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