Description
Product Name: | PRMT8 Polyclonal Antibody |
Product Code: | CAB2326 |
Reactivity: | Human, Mouse |
Applications: | Western blotting |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Reactivity: | Human, Mouse |
Tested Applications: | WB, ELISA |
Key Applications: | Western blotting |
Recommended Dilution: | WB 1:500-1:1000 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3. |
Positive Samples: | Jurkat, MCF7, SH-SY5Y |
Cellular Location: | Cell membrane, Cytoplasmic side, Lipid-anchor |
Arginine methylation is a widespread posttranslational modification mediated by arginine methyltransferases, such as PRMT8. Arginine methylation is involved in a number of cellular processes, including DNA repair, RNA transcription, signal transduction, protein compartmentalization, and possibly protein translation (Lee et al., 2005 [PubMed 16051612]).
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 200-380 of human PRMT8 (NP_062828.3). |
Sequence: | VIFAR DKWLK PGGLM FPDRA ALYVV AIEDR QYKDF KIHWW ENVYG FDMTC IRDVA MKEPL VDIVD PKQVV TNACL IKEVD IYTVK TEELS FTSAF CLQIQ RNDYV HALVT YFNIE FTKCH KKMGF STAPD APYTH WKQTV FYLED YLTVR RGEEI YGTIS MKPNA KNVRD LDFTV DLDFK G |
Synonyms: | HRMT1L3, HRMT1L4 |
Calculated MW: | 45kDa |
Observed MW: | 45kDa |