Description
Product Name: | PRMT4/CARM1 Monoclonal Antibody |
Product Code: | CAB21106 |
Reactivity: | Human, Mouse, Rat |
Applications: | Western blotting, Immunoprecipitation |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Clone No: | ARC52397 |
Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB, IP, ELISA |
Key Applications: | Western blotting, Immunoprecipitation |
Recommended Dilution: | WB 1:500-1:1000, IP 1:500-1:1000 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
Positive Samples: | MCF7, 293T, Mouse testis, Rat testis |
Cellular Location: | Cytoplasm, Nucleus |
This gene belongs to the protein arginine methyltransferase (PRMT) family. The encoded enzyme catalyzes the methylation of guanidino nitrogens of arginyl residues of proteins. The enzyme acts specifically on histones and other chromatin-associated proteins and is involved in regulation of gene expression. The enzyme may act in association with other proteins or within multi-protein complexes and may play a role in cell type-specific functions and cell lineage specification. A related pseudogene is located on chromosome 9.
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 486-603 of human PRMT4/CARM1 (NP_954592.1). |
Sequence: | GSHYT SPSEN MWNTG STYNL SSGMA VAGMP TAYDL SSVIA SGSSV GHNNL IPLAN TGIVN HTHSR MGSIM STGIV QGSSG AQGSG GGSTS AHYAV NSQFT MGGPA ISMAS PMSIP TNT |
Synonyms: | PRMT4 |
Calculated MW: | 66kDa |
Observed MW: | 60kDa/63kDa |