Description
Product Name: | PRDM10 Polyclonal Antibody |
Product Code: | CAB7822 |
Reactivity: | Human, Mouse |
Applications: | Western blotting |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Reactivity: | Human, Mouse |
Tested Applications: | WB, ELISA |
Key Applications: | Western blotting |
Recommended Dilution: | WB 1:500-1:2000 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Cellular Location: | Nucleus |
The protein encoded by this gene is a transcription factor that contains C2H2-type zinc-fingers. It also contains a positive regulatory domain, which has been found in several other zinc-finger transcription factors including those involved in B cell differentiation and tumor suppression. Studies of the mouse counterpart suggest that this protein may be involved in the development of the central nerve system (CNS), as well as in the pathogenesis of neuronal storage disease. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 600-870 of human PRDM10 (NP_064613.2). |
Sequence: | LDLLK DHVAI HINDG YFTCP TCKKR FPDFI QVKKH VRSFH SEKIY QCTEC DKAFC RPDKL RLHML RHSDR KDFLC STCGK QFKRK DKLRE HMQRM HNPER EAKKA DRISR SKTFK PRITS TDYDS FTFKC RLCMM GFRRR GMLVN HLSKR HPDMK IEEVP ELTLP IIKPN RDYFC QYCDK VYKSA SKRKA HILKN HPGAE LPPSI RKLRP AGPGE PDPML STHTQ LTGTI ATPPV CCPHC SKQYS SKTKM VQHIR KKHPE FAQLS NTIHT P |
Synonyms: | PFM7, TRIS |
Calculated MW: | 130kDa |
Observed MW: | Refer to figures |