PPP3CA Monoclonal Antibody [PAT1E11AT] (CPAB0694)
![PPP3CA Monoclonal Antibody [PAT1E11AT] (CPAB0694)](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/608x608/products/58914/64096/ppp3ca-monoclonal-antibody-pat1e11at-cpab0694__82782__41865.1706535258.jpg?c=1 "PPP3CA Monoclonal Antibody [PAT1E11AT] (CPAB0694)")
- SKU:
- CPAB0694
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Universal
- Host Species:
- Mouse
- Isotype:
- IgG2b
- Clone:
- PAT1E11AT
- Applications:
- WB
- Applications:
- ELISA
![PPP3CA Monoclonal Antibody [PAT1E11AT] (CPAB0694)](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/1280x1280/products/58914/64096/ppp3ca-monoclonal-antibody-pat1e11at-cpab0694__82782__41865.1706535258.jpg?c=1&imbypass=on "PPP3CA Monoclonal Antibody [PAT1E11AT] (CPAB0694)")
Description
system_update_alt Datasheet
| Product Name: | PPP3CA antibody |
| Product Sku: | CPAB0694 |
| Size: | 5μg |
| Host Species: | Mouse |
| Immunogen: | Anti-human PPP3CA mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human PPP3CA protein 1-511 amino acids purified from Ecoli. |
| Clone: | PAT1E11AT. |
| Reactivity: | Other bodies |
| Applications: | Western Blot, ELISA |
| Purification Method: | PPP3CA antibody was purified from mouse ascitic fluids by protein-A affinity chromatography. |
| Isotype: | IgG2b |
| Background: | PPP3CA (aka Calcineurin A) is a major soluble calmodulin binding protein in the brain and a Ca2+/calmodulin dependent serine/threonine protein phosphatase, with a relatively limited substrate specificity. PPP3CA activates the T cells of the immune system and can be blocked by drugs. PPP3CA activates NFATc (a transcription factor) by dephosphorylating it. The activated NFATc is subsequently translocated into the nucleus, where it upregulates the expression of interleukin 2. |
| Synonyms: | Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform, CAM-PRP catalytic subunit, Calmodulin-dependent calcineurin A subunit alpha isoform, PPP3CA, CALNA, CAN, CALN, CCN1, CNA1, PPP2B, CALNA1. |
| Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |
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