Description
Product Name: | PPP2R3C Polyclonal Antibody |
Product Code: | CAB10628 |
Reactivity: | Human |
Applications: | Western blotting |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Reactivity: | Human |
Tested Applications: | WB, ELISA |
Key Applications: | Western blotting |
Recommended Dilution: | WB 1:500-1:2000 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Cellular Location: | Cytoplasm, Nucleus |
This gene encodes a regulatory subunit of the serine/threonine phosphatase, protein phosphatase 2. This protein is localized to both nuclear and cytoplasmic regions depending on cell cycle phase. Homozygous conditional knockout mice for this gene exhibit reduced numbers and impaired proliferation of immune system B cells. This protein may regulate the expression of the P-glycoprotein ATP-binding cassette transporter through its phosphatase activity. Alternative splicing results in multiple transcript variants.
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-160 of human PPP2R3C (NP_060387.2). |
Sequence: | MDWKE VLRRR LATPN TCPNK KKSEQ ELKDE EMDLF TKYYS EWKGG RKNTN EFYKT IPRFY YRLPA EDEVL LQKLR EESRA VFLQR KSREL LDNEE LQNLW FLLDK HQTPP MIGEE AMINY ENFLK VGEKA GAKCK QFFTA KVFAK LLHTD SYGRI SIMQF |
Synonyms: | G4-1, G5pr, GDRM, MEGD, SPGF36, C14orf10 |
Calculated MW: | 53kDa |
Observed MW: | Refer to figures |