UniProt Protein Function: | PPP2R2C: The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. Belongs to the phosphatase 2A regulatory subunit B family. 4 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Protein phosphatase, regulatory subunit Chromosomal Location of Human Ortholog: 4p16.1 Molecular Function:protein binding |
NCBI Summary: | The product of this gene belongs to the phosphatase 2 regulatory subunit B family. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes a gamma isoform of the regulatory subunit B55 subfamily. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q9Y2T4 |
NCBI GenInfo Identifier: | 145559437 |
NCBI Gene ID: | 5522 |
NCBI Accession: | Q9Y2T4.4 |
UniProt Secondary Accession: | Q9Y2T4,Q7Z4V7, Q8NEC4, Q9H3G7, A8MSY7, B7Z3Y1, |
UniProt Related Accession: | Q9Y2T4 |
Molecular Weight: | 50,636 Da |
NCBI Full Name: | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B gamma isoform |
NCBI Synonym Full Names: | protein phosphatase 2 regulatory subunit Bgamma |
NCBI Official Symbol: | PPP2R2C |
NCBI Official Synonym Symbols: | PR52; PR55G; IMYPNO; IMYPNO1; B55-GAMMA |
NCBI Protein Information: | protein phosphatase 2, regulatory subunit B, gamma |
UniProt Protein Name: | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B gamma isoform |
UniProt Synonym Protein Names: | IMYPNO1; PP2A subunit B isoform B55-gamma; PP2A subunit B isoform PR55-gamma; PP2A subunit B isoform R2-gamma; PP2A subunit B isoform gamma |
Protein Family: | Serine/threonine-protein phosphatase |
UniProt Gene Name: | PPP2R2C |
UniProt Entry Name: | 2ABG_HUMAN |