PPP1R11 Antibody (PACO31756)
- SKU:
- PACO31756
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | PPP1R11 Antibody (PACO31756) |
| Antibody SKU: | PACO31756 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human E3 ubiquitin-protein ligase PPP1R11 protein (1-126AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human placenta tissue using PACO31756 at dilution of 1:100. |
| Background: | Atypical E3 ubiquitin-protein ligase which ubiquitinates TLR2 at 'Lys-754' leading to its degradation by the proteasome. Plays a role in regulating inflammatory cytokine release and gram-positive bacterial clearance by functioning, in part, through the ubiquitination and degradation of TLR2. Inhibitor of protein phosphatase 1. |
| Synonyms: | E3 ubiquitin-protein ligase PPP1R11 (EC 2.3.2.27) (Hemochromatosis candidate gene V protein) (HCG V) (Protein phosphatase 1 regulatory subunit 11) (Protein phosphatase inhibitor 3), PPP1R11, HCGV TCTE5 |
| UniProt Protein Function: | PPP1R11: Inhibitor of protein phosphatase 1.Protein type: Motility/polarity/chemotaxis; Protein phosphatase, regulatory subunitChromosomal Location of Human Ortholog: 6p22.1Cellular Component: cytoplasm; nucleus; protein phosphatase type 1 complexMolecular Function: protein binding; protein phosphatase 1 binding; type 1 serine/threonine specific protein phosphatase inhibitor activityBiological Process: negative regulation of phosphoprotein phosphatase activity |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a specific inhibitor of protein phosphatase-1 (PP1) with a differential sensitivity toward the metal-independent and metal-dependent forms of PP1. The gene is located within the major histocompatibility complex class I region on chromosome 6. [provided by RefSeq, Jul 2008] |
| UniProt Code: | O60927 |
| NCBI GenInfo Identifier: | 11386175 |
| NCBI Gene ID: | 6992 |
| NCBI Accession: | NP_068778.1 |
| UniProt Secondary Accession: | O60927 |
| UniProt Related Accession: | O60927 |
| Molecular Weight: | 41.3kD |
| NCBI Full Name: | protein phosphatase 1 regulatory subunit 11 |
| NCBI Synonym Full Names: | protein phosphatase 1 regulatory inhibitor subunit 11 |
| NCBI Official Symbol: | PPP1R11 |
| NCBI Official Synonym Symbols: | HCGV; IPP3; HCG-V; TCTE5; TCTEX5; CFAP255 |
| NCBI Protein Information: | protein phosphatase 1 regulatory subunit 11 |
| UniProt Protein Name: | Protein phosphatase 1 regulatory subunit 11 |
| UniProt Synonym Protein Names: | Hemochromatosis candidate gene V protein; HCG V; Protein phosphatase inhibitor 3 |
| Protein Family: | |
| UniProt Gene Name: | PPP1R11 |
| UniProt Entry Name: |
| Antibodies |
| PPP1R11 Antibody (PACO05185) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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