Description
system_update_alt Datasheet
| Product Name: | PPP1CA Antibody |
| Product Sku: | CPAB0159 |
| Size: | 5μg |
| Host Species: | Mouse |
| Immunogen: | Anti-human PPP1CA mAb, is derived from hybridization of mouse FO myeloma cells with spleen cells from BALB/c mice immunized with recombinant human PPP1CA amino acids 3-299 purified from Ecoli. |
| Clone: | P4G3AT. |
| Reactivity: | Human |
| Applications: | Western Blot, ELISA |
| Purification Method: | PPP1CA antibody was purified from mouse ascitic fluids by protein-G affinity chromatography. |
| Isotype: | IgG2a |
| Background: | PPP1CA is one of the 3 catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase which is involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Increased PP1 activity is detected in the end stage of heart failure. Studies in both human and mice suggest that PP1 is a significant regulator of cardiac function. Mouse studies also propose that PP1 functions as a suppressor of learning and memory. |
| Synonyms: | Serine/threonine-protein phosphatase PP1-alpha catalytic subunit, PP-1A, PPP1CA, PPP1A, protein phosphatase 1 catalytic subunit alpha isozyme, MGC1674, MGC15877, PP1alpha. |
| Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |