Description
system_update_alt Datasheet
Product Name: | PPM1F Antibody |
Product Sku: | CPAB0183 |
Size: | 5μg |
Host Species: | Mouse |
Immunogen: | Anti-human PPM1F mAb, clone PAT6D11AT, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human PPM1F protein 1-454 amino acids purified from Ecoli. |
Clone: | PAT6D11AT. |
Reactivity: | Human |
Applications: | Western Blot, ELISA |
Purification Method: | PPM1F antibody was purified from mouse ascitic fluids by protein-A affinity chromatography. |
Isotype: | IgG1 |
Background: | Protein Phosphatase 1F (PPM1F) is a part of the PP2C family of Ser/Thr protein phosphatases whose members are known to be negative regulators of cell stress response pathways. PPM1F interacts with Rho guanine nucleotide exchange factors (PIX), and as a result blocks the effects of p21-activated kinase 1 (PAK), a protein kinase mediating biological effects downstream of Rho GTPases. Calcium/calmodulin-dependent protein kinase II gamma (CAMK2G/CAMK-II) is one of the substrates of PPM1F. PPM1F is found to be an apoptosis Promoter. |
Synonyms: | Protein phosphatase 1F, Ca(2+)/calmodulin-dependent protein kinase phosphatase, CaM-kinase phosphatase, CaMKPase, Partner of PIX 2, Protein fem-2 homolog, hFem-2, KIAA0015, POPX2, PPM1F, CAMKP, FEM-2. |
Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |